League of Legends Seraphine players will likely find her to be a dynamic champion to build out properly. You will notice that her build is modified when she is up against either well-rounded or highly focused team comps, indicating you should not choose the same Seraphine build every single game of League of Legends
The most critical items to incorporate into your champ's build include: Echi di Helia, Scettro di cristallo di Rylai, and Incensiere ardente. Players who added these pieces in their kits had a greater winrate than those who worked towards other builds for Seraphine. Likewise, if you are trying to beat a well-mixed enemy team comp, you should strongly consider getting yourself the Stregoneria, and Ispirazione runes. In recent games, she won the greatest number of her games when equipped with these runes.
We calculated our Seraphine build guidance by analyzing 91.837 recently ranked LoL games with her in them. We only recommend the top winrate Seraphine builds that were built by ranked players enough times for us to suggest them. With so many games in our data, we are confident in our suggested builds.