LoL Senna players may find her to be a confusing champ to build out properly. You will find that her build changes when she is playing against either diversified or highly focused team comps, indicating you should not choose the same Senna build every game of League of Legends
The most critical items to use in your champion's build include: Eclissi, Ombra tagliente, and Arco di Assioma. Players who included these pieces in their kits had a much better winrate than those who used other builds for Senna. Moreover, if you are trying to beat a varied enemy team arrangement, you should really consider grabbing yourself the Precisione, and Stregoneria runes. In recent matches, she won the greatest percentage of her rounds when using these runes.
We came up with our Senna build recommendations by analyzing 192.916 recently ranked LoL rounds with her in them. We only advise the highest winrate Senna builds that have been built by ranked League players enough times for us to advise them. With so many matches in our data, we are confident in our suggested builds.