LoL Lissandra players may find her to be a confusing champ to build out properly. You'll see that her build changes when she is up against either well-rounded or specialized team comps, showing you shouldn't choose the same Lissandra build every round of League of Legends
The most critical items to use in your champion's build are: Dolore di Liandry, Copricapo di Rabadon, and Clessidra di Zhonya. Players who added these pieces in their builds had a higher winrate than those who tried for other builds for Lissandra. Moreover, if you are facing a mixed enemy team comp, you should strongly consider getting yourself the Stregoneria, and Dominazione runes. In recent games, she won the greatest percentage of her games when equipped with these runes.
We set our Lissandra build suggestions by examining 44.429 recently ranked League of Legends games with her in them. We only propose the top winrate Lissandra builds that were used by ranked League players enough times for us to propose them. With so many rounds in our data, we are confident in our recommended builds.