The top picks out of lane to counter Kassadin include Ziggs, Ezreal, and Kai'Sa. These picks are all great at countering Kassadin with win rates over 55%. Even if these Kassadin counter picks are not picked in the same position as you, it's not a good idea to choose him into any of these matchups. They will most often win against Kassadin.
Yet, if the opposite team choses either Nilah or Renata Glasc, you should seriously think about choosing him, as he easily beats these champs with win rates over 55% against both ofthem.
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