The best champs out of lane to counter Vex include Xayah, Kai'Sa, and Tristana. These are all good at countering Vex with decent win rates over 57%. Even if these Vex counter picks are not picked opposite your position, it's not a good idea to play them into one of these matchups. They will often destroy Vex.
Conversely, if the other team brings either Séraphine or Ivern, you should strongly think about picking them, as they easily dominates these champions with win rates over 53% against each ofthem.
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