The top picks globally to counter Ekko include Ziggs, Sivir, and Zeri. These are all great at countering Ekko with decent win rates over 54%. Even if these Ekko counter picks are not taken in the same position as you, it's not smart to choose him into one of these matchups. They will most often destroy Ekko.
Conversely, if the opposing team choses either Teemo or Olaf, you should strongly think about taking him, as he easily wins against these champions with win rates over 57% against each ofthem.
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