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The Zeri Karthus synergy stats shown here demonstrate the areas of their gameplay that do better (or worse) when paired with Karthus, compared to their overall stats. Significant differences are areas of focus that highlight how their gameplay changes when paired with this other champion.
Overall, Zeri sees a very large drop in their KDA (ratio of kills and assists to deaths) when paired with Karthus. His KDA fell from NaN to NaN. This worsening shows that Karthus helps Zeri perform poorer in competitive League of Legends games. Yet, the small difference shows that this performance change is only marginal.
When Zeri tries to synergize with Karthus, they sees a marginal improvement in their full damage output. This change could signal that Karthus helps provide cover for them to deal more damage or that his support also helps extend the round's duration. Similarly, when Zeri is played together with Karthus on the same team, he usually scores many fewer killing sprees than when they plays without Karthus. This is contrasting evidence that they is worse when playing synergisticly with Karthus.
Moreover, when Zeri plays with Karthus on the same team, they often takes more damage than when they fights alone. Receiving more damage could indicate that Karthus does a poor job of covering Zeri in teamfights.
There is no top synergy for Zeri that will always be their ideal synergy. However, overall, Karthus is a below average companion for Zeri. By locking into the same side as Zeri, he lowers their win rate by -2.2% to 44.0%. This demonstrates that there is a negative bond between Zeri and Karthus that allows them to perform worse together than alone.
Karthus has a greater difficulty than Zeri. That means you should be cautious when arranging Karthus allies to go into battle on the same side as, as they will require a greater level of skill to play well with you.
Fighting together, Zeri players should expect to observe an overall large increase in your team’s capacity to deal magical damage. Combined, these two can deal quite a lot of AP type damage.
Although, by grouping Zeri and Karthus together, you probably will not be giving your team enough engage potential. Make sure to pick other champions on your team that nullifies this relative hole in this pairing's playstyle.
Regardless of your Karthus ally's ability, you need to focus on maximizing your gold income, outlasting your enemies, and taking down objectives. If you heed this simple advice, you will do well, regardless.
If you would like to learn all of the intricacies of Zeri to synergize with Karthus during both the lane and mid / late game phases of League games, you should keep reading to pick up some more lessons on this champion pairing. If you mind the build and tips presented here, you will increase your win rate significantly.
The most important items to include in your Zeri and Karthus synergy build consist of Experimentelle Hexpanzerung, Runaans Wirbelsturm, and Titanische Hydra. When Zeri bought at least these three great items in their build, they did significantly better as an ally of Karthus than with many other commonly used item sets. In fact, Zeri boasted an average winrate of 44.0% when playing alongside Karthus with these items in their kit.
To have the best chance of annihilating your oponents, you should equip the Tödliches Tempo, Triumph, Legende: Eifer, Letztes Gefecht, Konditionierung, and Zuwachs runes from the Präzision and Entschlossenheit rune sets. Of all the rune sets that we analyzed for this champion pairing, this composite of runes resulted in the top win rate. In fact, these runes gave a 44.0% winrate overall.
If you want to see Zeri and Karthus collaboration tips and builds for a an individual player tier, feel free to choose one from the selection menu provided above. If viewing for the first time, the stats and tips and suggestions given are computed using all rounds run with these champions.