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The Neeko Karthus synergy stats shown here demonstrate the areas of her gameplay that do better (or worse) when paired with Karthus, compared to her overall stats. Significant differences are areas of focus that highlight how her gameplay changes when paired with this other champion.
Overall, Neeko sees a very large drop in her KDA (ratio of kills and assists to deaths) when paired with Karthus. His KDA worsened from NaN to NaN. This drop shows that Karthus helps Neeko perform not as well in competitive League matches. Yet, the small difference proves that this performance change is not very impactful.
When Neeko is an ally to Karthus, she observes a little decrease in her full damage dealt. This may indicate that Karthus does not support by providing cover for her to deal more damage or that his presence on the team also helps increase the match's duration. Similarly, when Neeko is played together with Karthus on the same side, he usually scores many fewer killing sprees than when she plays alone. This is contrasting evidence that she is worse when playing with Karthus.
Moreover, when Neeko plays with Karthus on the same side, she on average takes a little more damage than when she fights alone. Taking more damage could mean that Karthus does a poor job of covering Neeko during team fights.
There is no ideal companion for Neeko that will always be her best ally. Yet, overall, Karthus is a not very good ally for Neeko. By being on the same side as Neeko, he decreases their win rate by -2.9% to 46.5%. This shows that there is a bad strategic relationship between Neeko and Karthus that allows them to perform not as well together than alone.
Karthus has a greater difficulty than Neeko. That means Neeko players must be very careful when enlisting Karthus teammates to fight alongside, as they will need a greater level of skill to be able to play well with you.
Working alongside, you will likely witness an overall large increase in your team’s capacity to deal magical damage. Together, these champs can deal quite a lot of AP type damage.
Conversely, by pairing Neeko and Karthus together, you will not be giving your other allies a lot of attack damage. Plan to have other champs on your team that nullifies this hole in their abilities.
Regardless of the skill of your Karthus ally, you need to focus on maximizing your gold income, staying alive by avoiding foolish fights, and clearing objectives. If you heed this simple advice, you should do well, regardless.
To learn all of the intricacies of Neeko to work well with Karthus during both the lane and mid / late game phases of League of Legends rounds, you should keep reading to learn some more lessons on this champion pairing. If you listen to the build and stats shown above, you will grow your win rate significantly.
The best finished items to get in your Neeko and Karthus synergy build include Hextech-Raketengürtel, Schattenflamme, and Sturmblitz. When Neeko combined at least these three great items in her build, she performed much better when fighting alongside Karthus than with most other common item sets. In fact, Neeko had an average win rate of 46.5% helping carry Karthus with these items in her kit.
To have the highest chance of annihilating your oponents, Neeko players should equip the Arkaner Komet, Manafluss, Überlegenheit, Hitzewelle, Kekslieferung, and Kosmische Einsicht runes from the Zauberei and Inspiration rune sets. Of all the rune combinations we have analyed for Neeko and Karthus pairings, this mixture of runes yielded the greatest win rate. In fact, these runes averaged a 46.5% winrate overall.
By default, tips, stats, and builds on how to synergize Karthus with Neeko are shown for all ranked divisions. To scope the stats and builds to a distinct player tier, you may use the selection menu located earlier on the page.