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The Lillia Karthus synergy stats shown here demonstrate the areas of her gameplay that do better (or worse) when paired with Karthus, compared to her overall stats. Significant differences are areas of focus that highlight how her gameplay changes when paired with this other champion.
Overall, Lillia sees a large worsening in her KDA (ratio of kills and assists to deaths) when paired with Karthus. His KDA went down from NaN to NaN. This worsening shows that Karthus helps Lillia perform not as well in competitive League games. Yet, the small difference demonstrates that this performance change is only marginal.
When Lillia is paired with Karthus, she observes a little drop in her total damage dealt. This difference could indicate that Karthus does not provide cover for her to dish out more damage or that his support also helps increase the round's duration. Similarly, when Lillia is played alongside Karthus on the same team, he usually scores many fewer killing sprees compared to when she plays without Karthus. This is contrasting evidence that she is worse when playing with Karthus.
Moreover, when Lillia plays with Karthus on the same team, she typically receives a little more damage than when she fights alone. Taking more damage may indicate that Karthus does a poor job of covering Lillia during teamfights.
There is no top companion for Lillia that will no matter what be her #1 synergy. Yet, Karthus is a terrible companion for Lillia. By being on the same team as Lillia, he lowers their win rate by -4.1% to 50.0%. This shows that there is a very bad bond between Lillia and Karthus that allows them to perform worse together than alone.
Karthus has a lower difficulty than Lillia. That means you don't need to be very careful when enlisting Karthus teammates to play with, as they will need a lower level of skill to fight well with you.
Playing on the same side, you should expect to see an overall large increase in your team’s capability to to do a lot of AP damage. Combined, these champs can deal quite a lot of AP type damage.
Conversely, by bringing Lillia and Karthus together, you may not be granting your other allies enough anti-tank damage dealing potential. Make sure to bring other champs on your team that nullifies this hole in this pairing's kit.
Regardless of your Karthus ally's ability, you need to focus on maximizing your gold income, warding to avoid ambushes, and clearing objectives. If you do this, you should do well anyway.
To truly master Lillia in order to work well with Karthus during both the early game and mid / late game phases of LoL, you should keep reading to master some more tricks and insights into this champion pairing. If you use the build and stats presented here, you will increase your win rate by a lot.
The top items to use in your Lillia and Karthus synergy build include Rylais Kristallzepter, Kluftformer, and Liandrys Qual. When Lillia combined at least these three great items in her build, she did significantly better as an ally of Karthus than with most other common item sets. In fact, Lillia had an average winrate of 50.0% when playing alongside Karthus with these items in her kit.
To have the greatest probability of vanquishing your oponents, you should equip the Eroberer, Triumph, Legende: Zähigkeit, Gnadenstoß, Flinkheit, and Wasserlauf runes from the Präzision and Zauberei rune sets. Out of all the runes that we analyzed for this team composition, this sequence of runes resulted in the greatest win rate. In fact, these runes provided a 50.0% winrate overall.
By default, tips, statistics, and builds on how to pair Karthus with Lillia are presented for all ranked divisions. If you want to scope the statistics and builds to a distinct player tier, you may use the selection menu earlier in the counter matchup guide.