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The Karthus Zeri synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Zeri, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.
Overall, Karthus sees a large worsening in his KDA (ratio of kills and assists to deaths) when paired with Zeri. His KDA fell from NaN to NaN. This negative change shows that Zeri helps Karthus perform poorer in ranked LoL games. Yet, the small difference indicates that this performance change is only marginal.
When Karthus tries to synergize with Zeri, he observes a little drop in his complete damage output. This could indicate that Zeri does not provide protection for him to dish out more damage or that their support also helps extend the game's duration. Similarly, when Karthus is played alongside Zeri on the same side, he usually scores many fewer killing sprees than when he plays alone. This is contrasting evidence that he is worse when playing synergisticly with Zeri.
Moreover, when Karthus plays with Zeri on the same side, he usually takes a little more damage than when he plays alone. Receiving more damage could mean that Zeri does a poor job of covering Karthus in teamfights.
There is no universally accepted best companion for Karthus that will always be his top ally. However, Zeri is a very bad teammate for Karthus. By locking into the same team as Karthus, they drops their win rate by -3.3% to 44.0%. This proves that there is a terrible bond between Karthus and Zeri that results in them performing worse together than alone.
Zeri has a lower difficulty than Karthus. That means Karthus players don't need to be cautious when finding Zeri comrades to fight alongside, as they will require a lower level of skill to be able to work well with you.
Playing together, Karthus players will likely observe an overall large increase in your team’s capacity to deal magical damage. Together, these champions can deal quite a lot of AP type damage.
Conversely, by pairing Karthus and Zeri together, you may not be providing your team enough protection for burst damage. Plan to have other champions on your team that helps cover this hole in their kit.
Regardless of the skill of your Zeri ally, you need to focus on maximizing your gold income, warding to avoid ambushes, and taking down objectives. If you follow these simple suggestions, you will do well, regardless.
To learn all of the intricacies of Karthus to pair well with Zeri during both the lane and mid / late game phases of LoL, you should keep reading to learn a few extra lessons on this champion pairing. If you use the build and tips displayed above, you should grow your win rate significantly.
The most important items to include in your Karthus and Zeri synergy build include Rabadons Todeshaube, Bösartigkeit, and Liandrys Qual. When Karthus combined at least these three pieces in his build, he did significantly better when fighting alongside Zeri than with most other common builds. In fact, Karthus boasted an average win rate of 44.0% when synergizing his build and playstyle to Zeri with this build.
To have the best likelihood of coming out on top against your oponents, you should equip the Erstschlag, Magisches Schuhwerk, Zukunftsmarkt, Kosmische Einsicht, Argus' Vermächtnis, and Ultimativer Jäger runes from the Inspiration and Dominanz rune sets. Out of all the rune builds players chose for this champion pairing, this set of runes yielded the greatest win rate. In fact, these runes provided a 44.0% win rate overall.
If you need to get Karthus and Zeri cooperations tips and stats for a a particular division rank, feel free to choose one from the selection menu displayed above. By default, the statistics and guides shown are computed using every match run with these champs.