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The Karthus Vex synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Vex, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.
Overall, Karthus sees a very large drop in his KDA (ratio of kills and assists to deaths) when paired with Vex. His KDA went down from NaN to NaN. This drop shows that Vex helps Karthus perform not as well in ranked League rounds. Yet, the small difference demonstrates that this performance change is not very impactful.
When Karthus tries to synergize with Vex, he sees a small decrease in his full damage dealt. This may indicate that Vex does not support by providing protection for him to deal more damage or that their presence on the team also helps increase the match's duration. Similarly, when Karthus is played alongside Vex on the same team, he usually scores many fewer killing sprees compared to when he plays alone. This is contrasting evidence that he is worse when playing with Vex.
Additionally, when Karthus plays with Vex on the same team, he on average takes a little more damage than when he fights alone. Getting dealt more damage may mean that Vex does a poor job of covering Karthus during team fights.
There is no ideal companion for Karthus that will no matter what be his best teammate. However, overall, Vex is a below average teammate for Karthus. By being on the same team as Karthus, they drops their win rate by -1.9% to 45.4%. This demonstrates that there is a negative bond between Karthus and Vex that allows them to perform worse together than without each other.
Vex has a much lower diffuclty than Karthus. That means Karthus players don't need to be careful when enlisting Vex teammates to fight alongside, as they will need a much lower level of skill to be able to do well with you.
Fighting alongside, you will likely see an overall large increase in your team’s capability to to do a lot of AP damage. Combined, these two can blast through enemies with magic damage.
Conversely, by grouping Karthus and Vex together, you will not be providing your other allies a great deal of sustained damage output. Make sure to have other champions on your team that helps cover this hole in their capabilities.
Regardless of your Vex ally's skill level, you should focus on increasing your gold income, outlasting your enemies, and clearing objectives. If you follow these simple suggestions, you should do well, regardless.
To learn all of the intricacies of Karthus in order to work well with Vex during both the early game and mid / late game phases of League of Legends rounds, you should keep reading to master additional tips and tricks for this champion pairing. If you listen to the build and suggestions displayed here, you will increase your win rate significantly.
The best finished items to have in your Karthus and Vex synergy build include Rabadons Todeshaube, Bösartigkeit, and Schattenflamme. When Karthus combined at least these three pieces in his build, he did much better when fighting alongside Vex than with most other common item sets. In fact, Karthus boasted an average win rate of 45.4% when synergizing his build and playstyle to Vex with this build.
To have the highest chance of annihilating your oponents, Karthus players should equip the Erstschlag, Magisches Schuhwerk, Zukunftsmarkt, Kosmische Einsicht, Argus' Vermächtnis, and Ultimativer Jäger runes from the Inspiration and Dominanz rune sets. Out of all the rune builds players picked for Karthus and Vex pairings, this blending of runes resulted in the greatest win rate. Moreover, these runes averaged a 45.4% win rate overall.
By default, tips, stats, and builds on how to team up Vex with Karthus are shown for all skill levels, merged. If you want to scope the statistics and builds to a distinct division, you should use the selection menu at the top of this page.