LoL Zyra players may find her to be a dynamic character to build out properly. You'll see that her build changes when she is playing against either well-rounded or homogenous team comps, showing you should not choose the same Zyra build every single game of League of Legends
The most important items to use in your champ's build are: Liandrys Leid, Rabadons Todeshaube, and Splitter des Wahren Eises. Players who added these pieces in their gear had a higher winrate than those who used other Zyra builds. Moreover, if you are playing a well-mixed enemy team composition, you should really consider grabbing yourself the Zauberei, and Dominanz runes. In recent games, she won the largest percentage of her games when built with these runes.
We came up with our Zyra build guidance by analyzing 165.851 recently ranked LoL rounds with her in them. We only propose the highest winrate Zyra builds that have been built by ranked LoL players enough times for us to propose them. With so many games in our dataset, we are quite confident in our recommended builds.