League of Legends Senna players may find her to be a complex champ to build out properly. You will see that her build changes when she is playing against either generic or specialized team comps, showing you should not follow the same Senna build every single round of League of Legends
The most critical items to include in your champion's build include: Eklipse, Schattengleve, and Axiombogen. Players who added these pieces in their setups had a significantly better winrate than players who worked towards other Senna builds. Moreover, if you are trying to beat a well-mixed enemy team composition, you should strongly consider getting yourself the Präzision, and Zauberei runes. In recent matches, she won the largest fraction of her games when equipped with these runes.
We came up with our Senna build suggestions by examining 192.916 recently ranked League games with her selected. We only recommend the best winrate Senna builds that have been used by ranked LoL players enough times for us to reccomend them. With so many matches in our data, we are confident in our recommended builds.