LoL Nasus players will likely find him to be a complex champ to build out properly. You'll notice that his build is modified when he is fighting either generic or specialized team compositions, meaning you should not take the same Nasus build every single game of League of Legends
The most critical items to include in your champ's build include: Göttlicher Entzweier, Gefrorenes Herz, and Seryldas Bitterkeit. Players who added these pieces in their gear had a better win rate than those who used other builds for Nasus. Likewise, if you are fighting a well-mixed enemy team composition, you should really consider grabbing yourself the Inspiration, and Entschlossenheit runes. In recent games, he won the largest fraction of his matches when using these runes.
We established our Nasus build guidance by examining 108.049 recently ranked League of Legends games with him in them. We only propose the top winrate Nasus builds that have been built by ranked players enough times for us to propose them. With so many rounds in our data, we are quite confident in our recommended builds.