The best picks not in lane to counter Kayn include Ezreal, Kai'Sa, and Zeri. These are all great at countering Kayn with decent win rates over 56%. Even if these Kayn counter picks are not played in the same position as you, it's not smart to take him into these matchups. They will likely crush Kayn.
Yet, if the opposing team choses either Teemo or Seraphine, Kayn mains should strongly consider choosing him, as he easily dominates these selections with win rates over 52% against each ofthem.
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