League of Legends Annie players will likely find her to be a dynamic champ to build out properly. You will see that her build changes when she is up against either well-rounded or specialized team compositions, indicating you shouldn't take the same Annie build every single game of League of Legends
The most critical items to use in your champ's build are: Liandrys Leid, Rylais Kristallzepter, and Dämonische Umarmung. Those who added these items in their setups had a much higher win rate than players who worked towards other item builds for Annie. Moreover, if you are fighting a well-mixed enemy team composition, you should really consider grabbing her the Dominanz, and Zauberei runes. In recent matches, she won the largest fraction of her games when using these runes.
We established our Annie build suggestions by analyzing 34.863 recently ranked League rounds with her in them. We only advise the highest winrate Annie builds that were built by ranked gamers enough times for us to suggest them. With so many games in our data, we are quite confident in our recommended builds.