Seeds grant vision to your team.
Placing a seed in your spell's path after you have cast it gives you the best chance of having a seed in the proper spot.
Zyra is a great ambusher - look for opportunities to set a trap of seeds in brush, then lure enemies in.
Deny Vayne the opportunity to pin you against walls.
Vayne is fragile - turn the pressure up on her and she will be forced to play cautiously.
The stats provided here feature several important Zyra vs. Vayne counter statistics that can help us appreciate the differences between this set of champions. For instance, Zyra’s KDA ratio ([kills + assists] / deaths) of NaN is greater than Vayne’s KDA ratio of NaN, demonstrating that Zyra may be more central to her team's team fighting potential than Vayne. This observation is in large part fueled by the differences in assists.
Zyra often has a significantly smaller longest kill spree than her matchup does. Typically, she takes less damage than Vayne. This is usually reflective of different amounts of tankyness, but it can also indicate that the one champion has less agility and thus is not able to escape additional damage when engaged or poked.
Both LoL champs are great champions. Both champs have their pros and cons. In the game's current meta, Zyra usually wins when taking on Vayne, with a 52.6% win rate. Therefore, Zyra makes a good counter to Vayne.
While Zyra does have a higher winrate compared to Vayne, when they face off with one another, Zyra also has a lower learning curve that makes her a less time consuming champ to learn and master. You don't need to be too worried when picking Zyra into Vayneas her relative depth means that you may not be able to reach her full potential without a significant amount of practice beforehand.
Moreover, Zyra has some amount of utility and CC, a similar amount to Vayne. This often makes her just as valuable during team fights, especially when facing champions with a lot of burst damage.
While there isn't one best champion overall in League of Legends, in Zyra vs Vayne matchups, Zyra is the better champion with a noticably higher win rate, less champion complexity, and a similar amount of utility to help out your allies during late stage team fights.
Zyra is an above average counter to Vayne. You will do well by focussing your strategy on increasing your gold income and taking out objectives. If you are able to do that, you should do very well as Zyra against Vayne.
To learn all of the intricacies of Zyra in order to counter Vayne during both the lane and mid / late game phases of League of Legends, you should continue reading to pick up a few extra lessons on this matchup. If you mind the build and stats shown above, you will grow your win rate by a lot and be that much closer to League of Legends pro players.
Zyra often racks up less CS as Vayne. Champs who typically don't acquire many minion kills often don't need much CS to be valuable teammates, such as sup champs. These kinds of champions are able to scale well off of their abilities and first items alone. Yet, champs with large amounts of CS, such as hyper-carries, often need several high cost items to be effective. In either case, try to exceed the numbers shown on this page to do well.
The most important items to focus on in your Zyra versus Vayne build include Rylai's Crystal Scepter, Zaz'Zak's Realmspike, and Stormsurge. When Zyra included at least these three pieces in her build, she did much better vs Vayne than with most other commonly used counter builds. In fact, Zyra had an average win rate of 52.6% when countering Vayne with this build.
To have the best likelihood of coming out on top against Vayne as Zyra, Zyra players should use the Arcane Comet, Manaflow Band, Transcendence, Scorch, Relentless Hunter, and Taste of Blood runes from the Sorcery and Domination rune sets. Of all the rune combinations players used for Zyra vs Vayne clashes, this mixture of runes resulted in the best win rate. Moreover, these runes averaged a 52.6% win rate overall.
By default, tips, statistics, and builds on how to beat Vayne as Zyra are given for all ranked divisions combined. To filter the stats and builds to an individual player tier, you should use the selection menu located earlier on the page.