Kai'Sa is very vulnerable to getting outranged by mages and long range carries.
Make sure to place wards in your blind spots so you can see Kai'Sa coming.
Kai'Sa is very good at picking off isolated enemies. Stick together against her.
The stats shown on this page feature some valuable Zeri vs. Kai'Sa matchup statistics that can help you appreciate the distinctions between these two champs. Zeri’s KDA ratio ([kills + assists] / deaths) of NaN is more than Kai'Sa’s ratio of NaN, demonstrating that Zeri may be more central to their team's team fighting effectiveness than Kai'Sa..
Zeri usually has a similar longest killing spree as their enemy does. On average, they takes more damage than Kai'Sa. This often reflects different amounts of tankyness, but it can also show that the champ with higher health has less agility and thus is unable to kite away from further damage when poked or engaged.
Both League champs are great champions. Both champs have their strengths, weaknesses, and counters. In the game's current meta, Zeri usually loses when taking on Kai'Sa, with a 47.6% win rate. As a result, Zeri makes a bad counter to Kai'Sa.
While Zeri does have a lower win rate compared to Kai'Sa, when they face off with one another, Zeri also has a greater learning curve that makes them a more time consuming champion to learn. You should be very concerned when picking Zeri into Kai'Sa.
Moreover, Zeri has some amount of utility and CC, a similar amount to Kai'Sa. This often makes her just as valuable during team fights, especially when trying to counter champions with a lot of burst damage.
While there isn't one best champion overall in League of Legends, in Zeri vs Kai'Sa matchups, Kai'Sa is the better champion with a lower win rate, similar champion depth, and a similar amount of utility to help out your team members during teamfights.
Zeri is a terribly counter to Kai'Sa. Focus your actions on maximizing your CS and clearing objectives. If you are able to do that, you should hold your own as Zeri against Kai'Sa.
To learn all of the intricacies of Zeri to counter Kai'Sa during both the laning and mid / late game phases of League of Legends, you should continue reading to learn a few extra tips and tricks for this matchup. If you pay attention to the build and tips presented here, you will grow your win rate significantly and be closer to League of Legends pro players.
Zeri most often picks up a similar amount of CS compared to Kai'Sa. Champs who typically don't earn many minion kills typically don't need much CS to be effective, such as support champions. These kinds of champions are able to scale well off of their skills, stats, and first items alone. Yet, champs with a lot of CS, such as hyper-carries, often need several high cost items to be effective. In either case, try to exceed the values displayed here to do well.
The top items to prioritize in your Zeri versus Kai'Sa build consist of Bloodthirster, Experimental Hexplate, and Runaan's Hurricane. When Zeri bought at least these three pieces in their build, they performed significantly better against Kai'Sa than with many other common item sets. In fact, Zeri had an average winrate of 47.6% when playing against Kai'Sa with this build.
To have the best chance of crushing Kai'Sa as Zeri, you should equip the Lethal Tempo, Triumph, Legend: Alacrity, Last Stand, Conditioning, and Overgrowth runes from the Precision and Resolve rune sets. Of all the rune sets we have analyed for Zeri vs Kai'Sa LoL games, this order of runes yielded the greatest win rate. In fact, these runes provided a 47.6% winrate overall.
If you want to see Zeri versus Kai'Sa tips and builds for a a particular player tier, feel free to choose one from the selection menu shown above. If viewing for the first time, the stats and guides displayed are computed using every game finished with these champs.