Transfusion instantly deals damage to the enemy before healing Vladimir, making it one of the best last hitting tools in the game.
Cast Hemoplague where it will afflict the most units.
Sanguine Pool pops incoming missiles, so it can be used to dodge disables.
Deny Vayne the opportunity to pin you against walls.
Vayne is fragile - turn the pressure up on her and she will be forced to play cautiously.
The stats provided here clarify some vital Vladimir vs. Vayne matchup stats that may help you interpret the distinctions between the two. For instance, Vladimir’s KDA ratio ([kills + assists] / deaths) of NaN is greater than Vayne’s ratio of NaN, demonstrating that Vladimir may be more central to his team's team fighting capability than Vayne..
Vladimir usually has a similar longest kill spree as his enemy does. Typically, he receives more damage than Vayne. This commonly reflects different amounts of tankyness, yet it can also hint that the champ with more health has less mobility and thus is unable to escape further damage when engaged or poked.
Both League of Legends champions are great champions. Both champs have their strengths, weaknesses, and counters. In League's current meta, Vladimir usually fairs equally well when trying to fight Vayne, with a 50.3% win rate. Thus, Vladimir makes an ok counter for Vayne.
While Vladimir does have a higher win rate than Vayne, when on opposite teams, Vladimir also has a lower level of difficulty that makes him a less complex champion to learn. You still need to be cautious when picking Vladimir into Vayneas his relative depth means that you may not be able to unleash his full potential without a significant amount of practice beforehand.
Moreover, Vladimir also has almost no amount of utility and CC, a similar amount to Vayne. This often makes her just as valuable during teamfights, especially when trying to counter champions with a ton of burst damage.
While there isn't one best champion for every situation in League of Legends, in Vladimir vs Vayne matchups, Vladimir is the better champ with a similar win rate, less champion complexity, and a similar amount of utility to help out your allies during late stage team fights.
Vladimir is a decent counter for Vayne. You will do well by focussing your strategy on maximizing your CS and destroying objectives. If you do that, you should hold your own as Vladimir against Vayne.
If you would like to learn all of the intricacies of Vladimir in order to counter Vayne during both the early game and mid / late game phases of League of Legends, you should keep reading to gather a few extra lessons on this matchup. If you mind the build and suggestions shown above, you will increase your win rate significantly and be closer to League of Legends pro players.
Vladimir most often picks up a similar amount of CS compared to Vayne. Champions who on average don't earn much CS usualy don't have to have much CS to be valuable teammates, such as support champions. They are able to scale properly off of their abilities and first items alone. Yet, champions with large amounts of CS, such as hyper-carries, usually require many items to be effective. In either situation, try to do better than the values reported here to do well.
The best items to focus on in your Vladimir versus Vayne build include Rabadon's Deathcap, Zhonya's Hourglass, and Riftmaker. When Vladimir combined at least these three pieces in his build, he performed significantly better when facing Vayne than with most other commonly used item sets. In fact, Vladimir boasted an average win rate of 50.3% when playing against Vayne with these items in his kit.
To have the best likelihood of vanquishing Vayne as Vladimir, Vladimir players should use the Conqueror, Triumph, Legend: Tenacity, Last Stand, Transcendence, and Gathering Storm runes from the Precision and Sorcery rune sets. Of all the rune sets that we analyzed for Vladimir vs Vayne LoL games, this composite of runes yielded the best win rate. In fact, these runes averaged a 50.3% winrate overall.
By default, tips, stats, and builds on how to beat Vayne as Vladimir are displayed for all skill levels, merged. If you would like to scope the statistics and builds to a specific skill level, you may use the selection menu located earlier in the counter matchup guide.