Transfusion instantly deals damage to the enemy before healing Vladimir, making it one of the best last hitting tools in the game.
Cast Hemoplague where it will afflict the most units.
Sanguine Pool pops incoming missiles, so it can be used to dodge disables.
Karthus can cast spells for a short duration after he is killed. Move away from his corpse to be safe.
Make sure you always have enough health to survive Requiem, even if you have to go back to the base more frequently to heal.
The stat comparisons shown on this page feature some critical Vladimir vs. Karthus counter statistics that can help you realize the differences and similarities between the two. Vladimir’s KDA ratio ([kills + assists] / deaths) of NaN is better than Karthus’s KDA ratio of NaN, demonstrating that Vladimir may be more central to his team's team fighting capacity than Karthus..
Vladimir normally has a similar longest kill spree as his matchup does. On average, he receives more damage than Karthus. This commonly reflects different amounts of tankyness; however, it can also show that the champion with more health has less agility and thus is not able to escape further damage when poked or engaged.
Both LoL champions are great champions. Both champs have their strengths, weaknesses, and counters. In the game's current meta, Vladimir usually wins when playing against Karthus, with a 54.7% win rate. Therefore, Vladimir makes a great counter to Karthus.
While Vladimir does have a much higher win rate compared to Karthus, when facing one another, Vladimir also has a greater learning curve that makes him a more challenging champion to develop with. You should be be fine when picking Vladimir into Karthusas his relative depth means you may not be able to unleash his full potential without a lot of practice beforehand.
Additionally, Vladimir also has only a small amount of CC and other utility, a similar amount to Karthus. This often makes her just as valuable during team fights, especially when facing champions with a ton of burst damage.
While there isn't one best champion for every situation in League of Legends, in Vladimir vs Karthus matchups, Vladimir is the better champ with a noticably higher win rate, similar champion depth, and a similar amount of utility to help out your allied champions during late stage team fights.
Vladimir is a great counter to Karthus. You will do well by focussing your strategy on increasing your gold and cs and destroying objectives. If you can do that, you should be able to stand on your own as Vladimir against Karthus.
If you would like to learn all of the intricacies of Vladimir to counter Karthus during both the laning and mid / late game phases of League of Legends, you should continue reading to gather a few extra tips and tricks for this matchup. If you listen to the build and stats presented above, you will grow your win rate significantly and be closer to League of Legends pro players.
Vladimir usually picks up more CS compared to Karthus. Champions who typically don't earn much CS typically don't have to have much CS to be valuable teammates, such as support champions. They are able to scale well off of their skills, stats, and first items alone. Yet, champs with a lot of CS, such as hyper-carries, typically need several high cost items to be effective. In either case, try to surpass the values reported here to do well.
The best items to focus on in your Vladimir versus Karthus build include Rabadon's Deathcap, Cosmic Drive, and Riftmaker. When Vladimir used at least these three pieces in his build, he performed a lot better when facing Karthus than with most other common item sets. In fact, Vladimir had an average win rate of 54.7% battling Karthus with these items in his kit.
To have the greatest likelihood of annihilating Karthus as Vladimir, Vladimir players should equip the Phase Rush, Nimbus Cloak, Transcendence, Gathering Storm, Magical Footwear, and Cosmic Insight runes from the Sorcery and Inspiration rune sets. Out of all the rune combinations players chose for Vladimir vs Karthus counterpicks, this mix of runes yielded the greatest win rate. In fact, these runes averaged a 54.7% win rate overall.
If you need to see Vladimir versus Karthus tips and counter stats for a a specific division rank, feel free to select one from the selection menu above. At first, the stats and build suggestions given are computed using all matches run with both champs.