Kai'Sa is very vulnerable to getting outranged by mages and long range carries.
Make sure to place wards in your blind spots so you can see Kai'Sa coming.
Kai'Sa is very good at picking off isolated enemies. Stick together against her.
The stats provided here underscore several strategic Vex versus Kai'Sa counter stats that may help you explain the differences between these two champions. Vex’s KDA ratio ([kills + assists] / deaths) of NaN is better than Kai'Sa’s ratio of NaN, highlighting that Vex may be more central to their team's team fighting potential than Kai'Sa..
Vex typically has a similar longest kill spree as their opponent does. Typically, they receives a similar amount of damage to Kai'Sa. This typically indicates different amounts of tankyness; however, it can also illustrate that the one champion has less mobility and thus is not able to kite away from additional harm when poked or engaged.
Both LoL champions are great. Both champs have their strengths, weaknesses, and counters. In League's current meta, Vex usually wins when trying to fight Kai'Sa, with a 53.6% win rate. Therefore, Vex makes a great counter to Kai'Sa.
While Vex does have a higher win rate compared to Kai'Sa, when on opposite teams, Vex also has a much lower level of difficulty that makes them a less complex character to learn and master. You should be be fine when picking Vex into Kai'Sa.
Additionally, Vex has some amount of CC and other utility, a similar amount to Kai'Sa. This often makes her just as valuable during team fights, especially when trying to counter champions with a lot of burst damage.
While there isn't one best champion for every situation in League of Legends, in Vex vs Kai'Sa matchups, Vex is the better champion with a noticably higher win rate, less champion complexity, and a similar amount of utility to help out your teammates during late stage team fights.
Vex is a great counter to Kai'Sa. Make sure you focus your actions on increasing your gold income and clearing objectives. If you are able to do that, you should hold your own as Vex against Kai'Sa.
To truly master Vex in order to counter Kai'Sa during both the lane and mid / late game phases of League of Legends, you should keep reading to learn a few extra lessons on this matchup. If you pay attention to the build and tips shown here, you should increase your win rate significantly and be closer to League of Legends pro players.
Vex often picks up a similar amount of CS compared to Kai'Sa. Champions who typically don't take many minion kills often don't require much CS to be valuable teammates, such as sup champs. They are capable of scaling properly off of their skills, stats, and first items alone. Yet, champions with large amounts of CS, such as hyper-carries, typically require a lot of items to be effective. In either situation, try to do better than the numbers shown on this page to do well.
The top items to use in your Vex versus Kai'Sa build consist of Zhonya's Hourglass, Shadowflame, and Stormsurge. When Vex combined at least these three pieces in their build, they performed a lot better against Kai'Sa than with most other commonly used builds. In fact, Vex boasted an average win rate of 53.6% battling Kai'Sa with this build.
To have the best chance of crushing Kai'Sa as Vex, you should use the Dark Harvest, Taste of Blood, Eyeball Collection, Ultimate Hunter, Manaflow Band, and Transcendence runes from the Domination and Sorcery rune sets. Out of all the rune builds players picked for Vex vs Kai'Sa clashes, this blending of runes yielded the greatest win rate. Notably, these runes averaged a 53.6% win rate overall.
If you want to get Vex versus Kai'Sa tips and builds for a an individual skill level, feel free to select one from the selection menu shown above. By default, the statistics and guides displayed are calculated using all matches finished with these champs.