Be very careful about when to use Life Form Disintegration Ray. Many champions have abilities that can interrupt the spell.
Shooting Plasma Fission diagonally and splitting at maximum range allows you to hit opponents that are out of the range of the initial missile, but is more challenging to pull off.
When laning, use Void Rift to kill minions while building stacks of Organic Deconstruction on your opponent. You can then follow up with your other abilities.
Deny Vayne the opportunity to pin you against walls.
Vayne is fragile - turn the pressure up on her and she will be forced to play cautiously.
The stat comparisons shown here feature some influential Vel'Koz versus Vayne counter stats that may help you appreciate the differences between the pair. Vel'Koz’s KDA ratio ([kills + assists] / deaths) of NaN is more than Vayne’s KDA ratio of NaN, showing that Vel'Koz may be more central to his team's team fighting capability than Vayne..
Vel'Koz often has a slightly smaller longest kill spree than his opponent does. Typically, he takes less damage than Vayne. This is usually reflective of differing health capacities, yet it can also indicate that the champion with higher health has less mobility and thus is not able to kite away from further harm when engaged or poked.
Both League champions are great. Both have their strengths, weaknesses, and counters. In the game's current meta, Vel'Koz usually fairs equally well when trying to fight Vayne, with a 49.7% win rate. Therefore, Vel'Koz makes an ok counter to Vayne.
While Vel'Koz does have a lower winrate compared to Vayne, when facing one another, Vel'Koz also has a greater difficulty level that makes him a more complex champ to pick up and master. You still need to be cautious when picking Vel'Koz into Vayneas his relative depth means you may not be able to unleash his full potential without a lot of practice beforehand.
Moreover, Vel'Koz also has some amount of CC and other utility, a similar amount to Vayne. This often makes her just as valuable during team fights, especially when fighting champions with a lot of burst damage.
While there is not a single best champion in League of Legends, in Vel'Koz vs Vayne matchups, Vayne is the better champion with a similar win rate, similar champion depth, and a similar amount of utility to help out your allies during team fights.
Vel'Koz is a somewhat poor counter to Vayne. Focus your strategy on increasing your gold income and clearing objectives. If you do that, you should do very well as Vel'Koz against Vayne.
To truly master Vel'Koz in order to counter Vayne during both the laning and mid / late game phases of League of Legends, you should keep reading to learn a few extra tips and tricks for this matchup. If you pay attention to the build and tips shown above, you will grow your win rate significantly and be closer to League of Legends pro players.
Vel'Koz often gets less CS compared to Vayne. Champions who on average don't get many minion kills typically don't need much CS to be effective, such as support champions. These kinds of champions are able to scale properly off of their abilities and first items alone. Yet, champs with a lot of CS, such as hyper-carries, often have to have many items to be effective. In either case, try to exceed the numbers shown on this page to do well.
The top items to prioritize in your Vel'Koz versus Vayne build include Zaz'Zak's Realmspike, Shadowflame, and Liandry's Torment. When Vel'Koz bought at least these three items in his build, he did significantly better vs. Vayne than with most other typical counter builds. In fact, Vel'Koz boasted an average win rate of 49.7% battling Vayne with this build.
To have the highest probability of annihilating Vayne as Vel'Koz, Vel'Koz players should take the Arcane Comet, Manaflow Band, Transcendence, Scorch, Cheap Shot, and Ultimate Hunter runes from the Sorcery and Domination rune sets. Out of all the rune sets players chose for Vel'Koz vs Vayne face-offs, this blending of runes resulted in the greatest win rate. In fact, these runes averaged a 49.7% winrate overall.
If you would like to view Vel'Koz vs Vayne tips and matchup stats and build suggestions for a a particular division, feel free to choose one from the selection menu provided above. By default, the stats and strategies given are calculated using every match played with both champions.