Don't go in first to a large teamfight. Wait for your teammates to initiate.
Tumble has many uses, but it cannot pass over walls.
Condemn can be used to both pin targets to walls to ensure a kill, or to escape a pursuer.
The stat comparisons shown on this page highlight several significant Vayne versus Zeri counter statistics that may help us appreciate the distinctions between the two. Vayne’s KDA ratio ([kills + assists] / deaths) of NaN is more than Zeri’s KDA ratio of NaN, indicating that Vayne may be more central to her team's team fighting potential than Zeri..
Vayne typically has a similar longest killing spree as her foe does. On average, she takes a similar amount of damage to Zeri. This commonly reflects differing health capacities, but it can also illustrate that the champ with higher health has less agility and thus is unable to flee from further harm when poked or engaged.
Both League of Legends champions are great champions. Both have their strengths, weaknesses, and counters. In the game's current meta, Vayne usually wins when facing off against Zeri, with a 54.8% win rate. Therefore, Vayne makes a great counter for Zeri.
While Vayne does have a much higher win rate than Zeri, when facing one another, Vayne also has a greater learning curve that makes her a more difficult character to pick up and master. You should be be fine when picking Vayne into Zerias her relative depth means you may not be able to reach her full potential without a significant amount of practice beforehand.
Additionally, Vayne also has some amount of utility and CC, a similar amount to Zeri. This makes her just as valuable during team fights, especially when fighting champions with a lot of burst damage.
While there isn't one best champion in League of Legends, in Vayne vs Zeri matchups, Vayne is the better champ with a noticably higher win rate, more champion depth, and a similar amount of utility to help out your teammates during team fights.
Vayne is a great counter to Zeri. Make sure you focus your tactics on maximizing your gold and cs and taking out objectives. If you do that, you should hold your own as Vayne against Zeri.
If you would like to truly master Vayne to counter Zeri during both the early game and mid / late game phases of League of Legends, you should keep reading to pick up a few extra lessons on this matchup. If you listen to the build and suggestions presented here, you will grow your win rate by a lot and be closer to League of Legends pro players.
Vayne often racks up a similar amount of CS relative to Zeri. Champions who on average don't take much CS typically don't require much CS to be effective, such as supports. These kinds of champions are able to scale properly off of their skills, stats, and first items alone. Yet, champs with a lot of CS, such as hyper-carries, usually have to have a lot of items to be effective. In either situation, try to surpass the values displayed on this page to do well.
The ideal items to prioritize in your Vayne versus Zeri build include Blade of The Ruined King, Terminus, and Kraken Slayer. When Vayne used at least these three items in her build, she performed significantly better when facing Zeri than with many other typical counter builds. In fact, Vayne had an average winrate of 54.8% battling Zeri with this counter build.
To have the greatest likelihood of vanquishing Zeri as Vayne, you should use the Lethal Tempo, Triumph, Legend: Alacrity, Coup de Grace, Conditioning, and Overgrowth runes from the Precision and Resolve rune sets. Out of all the rune sets players picked for Vayne vs Zeri clashes, this blending of runes yielded the greatest win rate. Notably, these runes averaged a 54.8% winrate overall.
By default, tips, statistics, and builds on how to beat Zeri as Vayne are shown for all ranked divisions combined. To scope the stats and builds to a specific division, you can use the selection menu located earlier on the page.