Don't go in first to a large teamfight. Wait for your teammates to initiate.
Tumble has many uses, but it cannot pass over walls.
Condemn can be used to both pin targets to walls to ensure a kill, or to escape a pursuer.
Get boots early when playing against Syndra, they'll help you avoid many of her spells.
Attack Syndra after she's used Scatter the Weak, it has a long cooldown so she'll be vulnerable.
At max rank Syndra's spells gain bonus effects and change in appearance.
The stat comparisons provided here underscore several valuable Vayne against Syndra counter stats that can help us figure out the differences between these two champions. Vayne’s KDA ratio ([kills + assists] / deaths) of NaN is greater than Syndra’s ratio of NaN, highlighting that Vayne may be more central to her team's team fighting capability than Syndra..
Vayne typically has a similar longest killing spree as her foe does. On average, she takes more damage than Syndra. This is usually reflective of different amounts of tankyness; however, it can also indicate that the one champion has less agility and thus is not able to escape further damage when poked or engaged.
Both League of Legends champs are great. Both champs have their pros and cons. In League's current meta, Vayne usually fairs equally well when facing off against Syndra, with a 50.1% win rate. Thus, Vayne makes an ok counter to Syndra.
While Vayne does have a higher win rate compared to Syndra, when they face off with one another, Vayne also has a greater learning curve that makes her a more challenging character to pick up and master. You still need to be cautious when picking Vayne into Syndraas her relative depth means you may not be able to reach her full potential without a lot of practice beforehand.
Moreover, Vayne has some amount of CC and other utility, a similar amount to Syndra. This often makes her just as valuable during team fights, especially when fighting champions with a lot of burst damage.
While there isn't one best champion overall in League of Legends, in Vayne vs Syndra matchups, Vayne is the better champ with a similar win rate, similar champion depth, and a similar amount of utility to help out your team members during teamfights.
Vayne is a decent counter for Syndra. Focus your gameplay on keeping up your CS and taking out objectives. If you are able to do that, you should do very well as Vayne against Syndra.
If you would like to truly master Vayne in order to counter Syndra during both the early game and mid / late game phases of League of Legends, you should continue reading to pick up a few extra lessons on this matchup. If you pay attention to the build and tips displayed here, you will increase your win rate by a lot and be that much closer to League of Legends pro players.
Vayne usually accumulates a similar amount of CS as Syndra. Champs who on average don't get much CS typically don't need much CS to be valuable teammates, such as support champions. They are able to scale properly off of their abilities and first items alone. Yet, champs with large amounts of CS, such as hyper-carries, usually need several high cost items to be effective. In either case, try to surpass the values reported on this page to do well.
The top items to prioritize in your Vayne versus Syndra build include Guinsoo's Rageblade, Blade of The Ruined King, and Jak'Sho, The Protean. When Vayne included at least these three pieces in her build, she performed much better countering Syndra than with many other typical item sets. In fact, Vayne boasted an average win rate of 50.1% when playing against Syndra with these items in her kit.
To have the best probability of annihilating Syndra as Vayne, Vayne players should use the Press the Attack, Triumph, Legend: Alacrity, Coup de Grace, Taste of Blood, and Treasure Hunter runes from the Precision and Domination rune sets. Of all the rune builds players chose for Vayne vs Syndra counters, this blending of runes resulted in the highest win rate. In fact, these runes provided a 50.1% win rate overall.
By default, tips, stats, and builds on how to beat Syndra as Vayne are given for all skill levels, merged. To filter the stats and builds to a specific player tier, you may use the selection menu located at the top of this page.