Don't go in first to a large teamfight. Wait for your teammates to initiate.
Tumble has many uses, but it cannot pass over walls.
Condemn can be used to both pin targets to walls to ensure a kill, or to escape a pursuer.
Ryze is especially dangerous to opponents that are marked with Flux.
Use Realm Warp's windup time to figure out how to deal with what may be coming out of the portal.
Crowd controlling Ryze during Realm Warp's windup will cancel the portal.
The stat comparisons provided here emphasize several valuable Vayne versus Ryze matchup stats that can help you appreciate the differences between this set of champions. For instance, Vayne’s KDA ratio ([kills + assists] / deaths) of NaN is better than Ryze’s ratio of NaN, demonstrating that Vayne may be more central to her team's team fighting effectiveness than Ryze..
Vayne normally has a slightly larger longest killing spree than her counter does. On average, she takes less damage than Ryze. This often reflects different amounts of tankyness, but it can also illustrate that the champion with higher HP has less agility and thus is unable to flee from further harm when poked or engaged.
Both LoL champs are great. Both have their pros and cons. In the game's current meta, Vayne usually wins when taking on Ryze, with a 51.4% win rate. Thus, Vayne makes a good counter for Ryze.
While Vayne does have a higher winrate compared to Ryze, when they face off with one another, Vayne also has a greater difficulty level that makes her a more complex champion to develop with. You still need to be cautious when picking Vayne into Ryzeas her relative depth means you may not be able to reach her full potential without a significant amount of practice beforehand.
Furthermore, Vayne has some amount of CC and other utility, a similar amount to Ryze. This makes her just as valuable during team fights, especially when trying to counter champions with a lot of burst damage.
While there isn't a single best champion in League of Legends, in Vayne vs Ryze matchups, Vayne is the better champ with a higher win rate, more champion depth, and a similar amount of utility to help out your teammates during team fights.
Vayne is a decent counter for Ryze. You will do well by focussing your tactics on keeping up your CS and destroying objectives. If you are able to do that, you should do very well as Vayne against Ryze.
If you would like to learn all of the intricacies of Vayne in order to counter Ryze during both the early game and mid / late game phases of League of Legends, you should continue reading to gather a few extra lessons on this matchup. If you pay attention to the build and suggestions shown here, you will increase your win rate by a lot and be that much closer to League of Legends pro players.
Vayne on average racks up a similar amount of CS relative to Ryze. Champions who typically don't earn much CS usualy don't require much CS to be valuable teammates, such as sup champs. These kinds of champions are able to scale well off of their abilities and first items alone. Yet, champs with a lot of CS, such as hyper-carries, usually require a lot of items to be effective. In either situation, try to surpass the values displayed on this page to do well.
The most important items to have in your Vayne versus Ryze build include Wit's End, Guinsoo's Rageblade, and Terminus. When Vayne used at least these three pieces in her build, she did significantly better when fighting Ryze than with most other commonly used builds. In fact, Vayne boasted an average winrate of 51.4% when countering Ryze with this counter build.
To have the best likelihood of coming out on top against Ryze as Vayne, Vayne players should equip the Lethal Tempo, Triumph, Legend: Alacrity, Coup de Grace, Conditioning, and Overgrowth runes from the Precision and Resolve rune sets. Out of all the rune combinations players picked for Vayne vs Ryze LoL games, this mix of runes resulted in the best win rate. Notably, these runes provided a 51.4% win rate overall.
By default, tips, statistics, and builds on how to beat Ryze as Vayne are presented for all skill levels, merged. If you want to filter the stats and builds to a distinct skill level, you can use the selection menu located above.