Don't go in first to a large teamfight. Wait for your teammates to initiate.
Tumble has many uses, but it cannot pass over walls.
Condemn can be used to both pin targets to walls to ensure a kill, or to escape a pursuer.
When Rek'Sai is near, she can see the position of you and your allies, but only if you're moving.
If you see one of Rek'Sai's tunnels, briefly stand on one of the entrances to destroy it.
Rek'Sai's Furious Bite gains damage as she builds Fury. Be very careful around her when her Fury is full.
The stats shown on this page underscore several vital Vayne against Rek'Sai matchup stats that may help us realize the differences and similarities between the pair. For instance, Vayne’s KDA ratio ([kills + assists] / deaths) of NaN is greater than Rek'Sai’s KDA ratio of NaN, demonstrating that Vayne may be more central to her team's team fighting potential than Rek'Sai..
Vayne usually has a similar longest kill spree as her opponent does. Typically, she receives less damage than Rek'Sai. This is usually reflective of different amounts of tankyness, yet it can also hint that the champ with increased health has less agility and thus is unable to escape further damage when poked or engaged.
Both LoL champs are great. Both have their strengths, weaknesses, and counters. In the game's current meta, Vayne usually wins when trying to fight Rek'Sai, with a 52.6% win rate. Therefore, Vayne makes a good counter for Rek'Sai.
While Vayne does have a higher winrate than Rek'Sai, when facing one another, Vayne also has a much greater level of difficulty that makes her a more time consuming champ to learn. You don't need to be too worried when picking Vayne into Rek'Saias her relative depth means you may not be able to reach her full potential without a lot of practice beforehand.
Furthermore, Vayne has some amount of CC and other utility, a similar amount to Rek'Sai. This often makes her just as valuable during team fights, especially when trying to counter champions with a ton of burst damage.
While there isn't a single best champion for every situation in League of Legends, in Vayne vs Rek'Sai matchups, Vayne is the better champ with a noticably higher win rate, more champion depth, and a similar amount of utility to help out your allies during team fights.
Vayne is a good counter to Rek'Sai. You will do well by focussing your actions on maximizing your gold income and taking out objectives. If you are able to do that, you should be able to stand on your own as Vayne against Rek'Sai.
To truly master Vayne in order to counter Rek'Sai during both the early game and mid / late game phases of League of Legends, you should keep reading to pick up a few extra tricks and insights into this matchup. If you mind the build and suggestions presented above, you will grow your win rate significantly and be that much closer to League of Legends pro players.
Vayne usually racks up much more CS relative to Rek'Sai. Champs who typically don't earn much CS usualy don't require much CS to be effective, such as support champions. They are able to scale properly off of their abilities and first items alone. Yet, champions with a lot of CS, such as hyper-carries, typically have to have several high cost items to be effective. In either situation, try to exceed the numbers reported here to do well.
The most important items to focus on in your Vayne versus Rek'Sai build include Wit's End, Blade of The Ruined King, and Terminus. When Vayne bought at least these three items in her build, she did much better when facing Rek'Sai than with most other commonly used item sets. In fact, Vayne had an average win rate of 52.6% battling Rek'Sai with this build.
To have the greatest chance of defeating Rek'Sai as Vayne, you should use the Lethal Tempo, Triumph, Legend: Alacrity, Coup de Grace, Conditioning, and Overgrowth runes from the Precision and Resolve rune sets. Of all the runes that we analyzed for Vayne vs Rek'Sai clashes, this sequence of runes yielded the highest win rate. Moreover, these runes averaged a 52.6% winrate overall.
By default, tips, stats, and builds on how to beat Rek'Sai as Vayne are shown for all ranked divisions combined. If you would like to filter the stats and builds to an individual skill level, you can use the selection menu located earlier on the page.