Don't go in first to a large teamfight. Wait for your teammates to initiate.
Tumble has many uses, but it cannot pass over walls.
Condemn can be used to both pin targets to walls to ensure a kill, or to escape a pursuer.
Mordekaiser builds up a powerful damage aura when fighting champions, so keep your distance.
Realm of Death will cut you off from your teammates completely. Try to save mobility spells to escape Mordekaiser once inside
Damage he deals can be converted into a large shield, and consumed for health
The stats shown on this page underscore several important Vayne versus Mordekaiser matchup statistics that can help us understand the differences between the two. As an example, Vayne’s KDA ratio ([kills + assists] / deaths) of NaN is greater than Mordekaiser’s KDA ratio of NaN, indicating that Vayne may be more central to her team's team fighting effectiveness than Mordekaiser..
Vayne normally has a similar longest kill spree as her enemy does. Typically, she takes less damage than Mordekaiser. This is usually reflective of differing health capacities, but it can also indicate that the one champion has less mobility and thus is unable to flee from additional harm when poked or engaged.
Both League of Legends champs are great champions. Both champs have their strengths, weaknesses, and counters. In League's current meta, Vayne usually fairs equally well when taking on Mordekaiser, with a 49.3% win rate. As a result, Vayne makes an ok counter to Mordekaiser.
While Vayne does have a lower win rate compared to Mordekaiser, when on opposite teams, Vayne also has a much greater learning curve that makes her a more time consuming character to learn. You should be careful when picking Vayne into Mordekaiseras her relative depth means you may not be able to reach her full potential without a lot of practice beforehand.
Additionally, Vayne also has some amount of CC and other utility, a similar amount to Mordekaiser. This makes her just as valuable during teamfights, especially when trying to counter champions with a ton of burst damage.
While there is not a single best champion overall in League of Legends, in Vayne vs Mordekaiser matchups, Mordekaiser is the better champion with a similar win rate, more champion depth, and a similar amount of utility to help out your teammates during teamfights.
Vayne is a somewhat poor counter to Mordekaiser. Make sure you focus your strategy on keeping up your gold income and clearing objectives. If you can do that, you should hold your own as Vayne against Mordekaiser.
If you would like to learn all of the intricacies of Vayne to counter Mordekaiser during both the lane and mid / late game phases of League of Legends, you should keep reading to pick up a few extra tricks and insights into this matchup. If you listen to the build and tips presented above, you should grow your win rate significantly and be closer to League of Legends pro players.
Vayne most often accumulates a similar amount of CS compared to Mordekaiser. Champions who typically don't get much CS usualy don't require much CS to be valuable teammates, such as supports. These kinds of champions are capable of scaling well off of their abilities and first items alone. Yet, champions with a lot of CS, such as hyper-carries, usually have to have many items to be effective. In either situation, try to do better than the values shown here to do well.
The most crucial items to focus on in your Vayne versus Mordekaiser build consist of Wit's End, Blade of The Ruined King, and Kraken Slayer. When Vayne used at least these three items in her build, she did significantly better when facing Mordekaiser than with many other typical counter builds. In fact, Vayne had an average winrate of 49.3% when countering Mordekaiser with this build.
To have the highest probability of beating Mordekaiser as Vayne, Vayne players should equip the Fleet Footwork, Triumph, Legend: Alacrity, Coup de Grace, Magical Footwear, and Biscuit Delivery runes from the Precision and Inspiration rune sets. Out of all the runes players picked for Vayne vs Mordekaiser clashes, this mixture of runes yielded the greatest win rate. Notably, these runes averaged a 49.3% win rate overall.
If you need to view Vayne vs Mordekaiser tips and counter stats for a a particular player tier, feel free to choose one from the selection menu above. By default, the stats and guides given are computed using all rounds run with both champs.