Don't go in first to a large teamfight. Wait for your teammates to initiate.
Tumble has many uses, but it cannot pass over walls.
Condemn can be used to both pin targets to walls to ensure a kill, or to escape a pursuer.
Try to coordinate high-damage abilities with your allies right after Dr. Mundo uses his ultimate, but if you're unable to kill him quickly with burst he will heal through the damage.
Try casting Ignite when Dr. Mundo uses Sadism to negate a large portion of its healing.
The stats shown here feature some vital Vayne vs. Dr. Mundo matchup stats that can help us appreciate the differences and similarities between these two champs. Vayne’s KDA ratio ([kills + assists] / deaths) of NaN is better than Dr. Mundo’s KDA ratio of NaN, highlighting that Vayne may be more central to her team's team fighting capacity than Dr. Mundo. This observation is in large part caused by the difference in kills.
Vayne typically has a much larger longest killing spree than her counter does. Typically, she takes less damage than Dr. Mundo. This commonly reflects different amounts of tankyness, but it can also illustrate that the one champ has less agility and thus is not able to flee from further damage when poked or engaged.
Both League champions are great champions. Both champs have their strengths, weaknesses, and counters. In the game's current meta, Vayne usually wins when trying to fight Dr. Mundo, with a 51.4% win rate. As a result, Vayne makes a good counter to Dr. Mundo.
While Vayne does have a higher winrate than Dr. Mundo, when facing one another, Vayne also has a much greater level of difficulty that makes her a more time consuming champ to pick up and master. You should be careful when picking Vayne into Dr. Mundoas her relative depth means that you may not be able to reach her full potential without a significant amount of practice beforehand.
Moreover, Vayne has some amount of utility and CC, a similar amount to Dr. Mundo. This makes her just as valuable during team fights, especially when trying to counter champions with a lot of burst damage.
While there is not one best champion for every situation in League of Legends, in Vayne vs Dr. Mundo matchups, Vayne is the better champ with a higher win rate, more champion depth, and a similar amount of utility to help out your teammates during teamfights.
Vayne is a decent counter for Dr. Mundo. You will do well by focussing your play on maximizing your gold income and taking out objectives. If you are able to do that, you should be able to stand on your own as Vayne against Dr. Mundo.
If you would like to truly master Vayne in order to counter Dr. Mundo during both the lane and mid / late game phases of League of Legends, you should continue reading to pick up a few extra lessons on this matchup. If you pay attention to the build and tips presented above, you should grow your win rate significantly and be closer to League of Legends pro players.
Vayne often accumulates a similar amount of CS compared to Dr. Mundo. Champions who typically don't acquire many minion kills usualy don't need much CS to be effective, such as support champions. These kinds of champions are able to scale well off of their skills, stats, and first items alone. Yet, champions with a lot of CS, such as hyper-carries, usually have to have many items to be effective. In either case, try to do better than the values reported on this page to do well.
The most crucial items to use in your Vayne versus Dr. Mundo build include Statikk Shiv, Blade of The Ruined King, and Terminus. When Vayne combined at least these three items in her build, she did a lot better when facing Dr. Mundo than with most other commonly used item sets. In fact, Vayne had an average winrate of 51.4% when countering Dr. Mundo with this counter build.
To have the best likelihood of crushing Dr. Mundo as Vayne, Vayne players should take the Lethal Tempo, Triumph, Legend: Alacrity, Coup de Grace, Conditioning, and Overgrowth runes from the Precision and Resolve rune sets. Of all the rune builds players picked for Vayne vs Dr. Mundo face-offs, this combination of runes resulted in the best win rate. Moreover, these runes averaged a 51.4% winrate overall.
If you need to see Vayne x Dr. Mundo tips and builds for a a specific division, please choose one from the selection menu shown above. If viewing for the first time, the stats and strategies displayed are calculated using all rounds finished with these champions.