Don't go in first to a large teamfight. Wait for your teammates to initiate.
Tumble has many uses, but it cannot pass over walls.
Condemn can be used to both pin targets to walls to ensure a kill, or to escape a pursuer.
Keep behind allied minions if Caitlyn is harassing you with Piltover Peacemaker (it deals less damage with each subsequent target).
You can intercept Ace in the Hole's missile from hitting an ally if you stand in its path.
The stat comparisons shown on this page underscore several vital Vayne versus Caitlyn counter statistics that can help us realize the distinctions between the pair. Vayne’s KDA ratio ([kills + assists] / deaths) of NaN is greater than Caitlyn’s ratio of NaN, indicating that Vayne may be more central to her team's team fighting capacity than Caitlyn..
Vayne usually has a similar longest kill spree as her enemy does. Commonly, she takes a similar amount of damage to Caitlyn. This typically indicates differing health capacities; however, it can also imply that the one champion has less agility and thus is not able to escape further harm when engaged or poked.
Both League of Legends champions are great. Both have their pros and cons. In the game's current meta, Vayne usually fairs equally well when taking on Caitlyn, with a 50.4% win rate. As a result, Vayne makes an ok counter for Caitlyn.
While Vayne does have a higher win rate compared to Caitlyn, when they face off with one another, Vayne also has a greater level of difficulty that makes her a more challenging character to learn and master. You should be careful when picking Vayne into Caitlynas her relative depth means you may not be able to unleash her full potential without a lot of practice beforehand.
Additionally, Vayne also has some amount of CC and other utility, a similar amount to Caitlyn. This often makes her just as valuable during teamfights, especially when facing champions with a ton of burst damage.
While there is not one best champion overall in League of Legends, in Vayne vs Caitlyn matchups, Vayne is the better champ with a similar win rate, more champion depth, and a similar amount of utility to help out your teammates during team fights.
Vayne is a decent counter to Caitlyn. Make sure you focus your actions on keeping up your CS and taking out objectives. If you can do that, you should do very well as Vayne against Caitlyn.
To truly master Vayne in order to counter Caitlyn during both the laning and mid / late game phases of League of Legends, you should keep reading to gather a few extra lessons on this matchup. If you mind the build and suggestions presented above, you should increase your win rate by a lot and be that much closer to League of Legends pro players.
Vayne most often accumulates a similar amount of CS as Caitlyn. Champs who on average don't get much CS often don't require much CS to be effective, such as supports. They are capable of scaling well off of their abilities and first items alone. Yet, champions with large amounts of CS, such as hyper-carries, typically have to have many items to be effective. In either case, try to surpass the numbers reported here to do well.
The most important items to use in your Vayne versus Caitlyn build include Bloodthirster, Wit's End, and Guinsoo's Rageblade. When Vayne bought at least these three pieces in her build, she did a lot better vs Caitlyn than with many other typical counter builds. In fact, Vayne boasted an average win rate of 50.4% battling Caitlyn with this counter build.
To have the best chance of crushing Caitlyn as Vayne, you should take the Lethal Tempo, Triumph, Legend: Alacrity, Coup de Grace, Overgrowth, and Conditioning runes from the Precision and Resolve rune sets. Of all the rune sets that we analyzed for Vayne vs Caitlyn fights, this order of runes resulted in the highest win rate. Moreover, these runes provided a 50.4% winrate overall.
By default, tips, stats, and builds on how to beat Caitlyn as Vayne are displayed for all skill levels, merged. If you would like to narrow the stats and builds to an individual rank, you can use the selection menu located earlier in the counter matchup guide.