Don't go in first to a large teamfight. Wait for your teammates to initiate.
Tumble has many uses, but it cannot pass over walls.
Condemn can be used to both pin targets to walls to ensure a kill, or to escape a pursuer.
Try to gank Anivia when she's laning. With multiple people, it is easier to ensure that her egg dies.
If you're playing a ranged champion, stay far enough away from Anivia so you can dodge Flash Frost more easily.
Try to fight Anivia in the lanes. In the jungle she can block pathways with lower ranks of Crystallize.
The stat comparisons shown on this page show some significant Vayne versus Anivia counter statistics that can help you understand the distinctions between the pair. For instance, Vayne’s KDA ratio ([kills + assists] / deaths) of NaN is better than Anivia’s KDA ratio of NaN, highlighting that Vayne may be more central to her team's team fighting effectiveness than Anivia..
Vayne normally has a slightly larger longest killing spree than her counter does. Commonly, she receives less damage than Anivia. This often reflects different amounts of tankyness, but it can also hint that the one champion has less mobility and thus is not able to kite away from additional damage when poked or engaged.
Both League of Legends champs are great champions. Both have their pros and cons. In the game's current meta, Vayne usually fairs equally well when taking on Anivia, with a 50.0% win rate. Thus, Vayne makes an ok counter for Anivia.
While Vayne does have a higher win rate than Anivia, when they face off with one another, Vayne also has a lower difficulty level that makes her a less challenging champion to learn. You should be careful when picking Vayne into Aniviaas her relative depth means you may not be able to unleash her full potential without a significant amount of practice beforehand.
Furthermore, Vayne has some amount of utility and CC, a similar amount to Anivia. This makes her just as valuable during teamfights, especially when trying to counter champions with a ton of burst damage.
While there is not a single best champion overall in League of Legends, in Vayne vs Anivia matchups, Anivia is the better champion with a similar win rate, less champion complexity, and a similar amount of utility to help out your allied champions during team fights.
Vayne is a decent counter for Anivia. You will do well by focussing your play on keeping up your CS and taking out objectives. If you are able to do that, you should be able to stand on your own as Vayne against Anivia.
To learn all of the intricacies of Vayne to counter Anivia during both the lane and mid / late game phases of League of Legends, you should keep reading to pick up a few extra tricks and insights into this matchup. If you pay attention to the build and suggestions presented here, you will increase your win rate significantly and be closer to League of Legends pro players.
Vayne typically gets a similar amount of CS compared to Anivia. Champs who typically don't take much CS often don't have to have much CS to be valuable teammates, such as supports. They are able to scale properly off of their skills, stats, and first items alone. Yet, champions with a lot of CS, such as hyper-carries, usually have to have a lot of items to be effective. In either case, try to surpass the values shown on this page to do well.
The most important items to use in your Vayne versus Anivia build consist of Guardian Angel, Blade of The Ruined King, and Terminus. When Vayne incorporated at least these three items in her build, she performed significantly better vs Anivia than with most other commonly used item sets. In fact, Vayne had an average winrate of 50.0% when countering Anivia with this counter build.
To have the best probability of vanquishing Anivia as Vayne, you should take the Lethal Tempo, Triumph, Legend: Alacrity, Coup de Grace, Conditioning, and Overgrowth runes from the Precision and Resolve rune sets. Out of all the runes players used for Vayne vs Anivia counter picks, this sequence of runes resulted in the best win rate. In fact, these runes gave a 50.0% winrate overall.
By default, tips, statistics, and builds on how to beat Anivia as Vayne are displayed for every ranked division. If you want to scope the statistics and builds to a specific skill level, you can use the selection menu earlier on the page.