Contaminate has a large range; apply as many stacks of Deadly Venom as possible before using it.
You can catch up to an enemy out of attack range with Venom Cask.
Twitch's Attack Speed is among the highest in the game; try purchasing items with on-hit effects such as Black Cleaver or Wit's End.
Get boots early when playing against Syndra, they'll help you avoid many of her spells.
Attack Syndra after she's used Scatter the Weak, it has a long cooldown so she'll be vulnerable.
At max rank Syndra's spells gain bonus effects and change in appearance.
The stats provided here clarify some strategic Twitch versus Syndra counter stats that can help us grasp the differences and similarities between the pair. As an example, Twitch’s KDA ratio ([kills + assists] / deaths) of NaN is greater than Syndra’s KDA ratio of NaN, indicating that Twitch may be more central to his team's team fighting effectiveness than Syndra..
Twitch often has a slightly larger longest killing spree than his enemy does. Commonly, he receives more damage than Syndra. This often reflects differing health capacities, yet it can also hint that the one champion has less mobility and thus is unable to escape additional harm when poked or engaged.
Both LoL champs are great champions. Both have their pros and cons. In the game's current meta, Twitch usually wins when facing off against Syndra, with a 52.5% win rate. Therefore, Twitch makes a good counter for Syndra.
While Twitch does have a higher win rate than Syndra, when facing one another, Twitch also has a lower learning curve that makes him a less complex champion to pick up and master. You should be be fine when picking Twitch into Syndra.
Furthermore, Twitch has almost no amount of CC and other utility, a similar amount to Syndra. This makes her just as valuable during team fights, especially when facing champions with a ton of burst damage.
While there is not one best champion in League of Legends, in Twitch vs Syndra matchups, Twitch is the better champ with a noticably higher win rate, less champion complexity, and a similar amount of utility to help out your allies during teamfights.
Twitch is a good counter to Syndra. Focus your gameplay on increasing your CS and clearing objectives. If you can do that, you should do very well as Twitch against Syndra.
If you would like to learn all of the intricacies of Twitch to counter Syndra during both the early game and mid / late game phases of League of Legends, you should continue reading to gather a few extra tips and tricks for this matchup. If you pay attention to the build and tips shown here, you should grow your win rate significantly and be closer to League of Legends pro players.
Twitch often picks up a similar amount of CS as Syndra. Champs who on average don't earn many minion kills often don't have to have much CS to be valuable teammates, such as support champions. They are capable of scaling properly off of their skills, stats, and first items alone. Yet, champs with large amounts of CS, such as hyper-carries, often require several high cost items to be effective. In either situation, try to do better than the values shown on this page to do well.
The best items to prioritize in your Twitch versus Syndra build consist of Runaan's Hurricane, Wit's End, and Terminus. When Twitch bought at least these three items in his build, he did significantly better vs. Syndra than with many other common item sets. In fact, Twitch boasted an average winrate of 52.5% when playing against Syndra with this build.
To have the highest probability of annihilating Syndra as Twitch, Twitch players should take the Lethal Tempo, Presence of Mind, Legend: Alacrity, Coup de Grace, Taste of Blood, and Treasure Hunter runes from the Precision and Domination rune sets. Of all the rune sets we have analyed for Twitch vs Syndra battles, this order of runes yielded the highest win rate. In fact, these runes gave a 52.5% winrate overall.
By default, tips, statistics, and builds on how to beat Syndra as Twitch are presented for all ranked divisions. To scope the stats and builds to a particular rank, you may use the selection menu located above.