Contaminate has a large range; apply as many stacks of Deadly Venom as possible before using it.
You can catch up to an enemy out of attack range with Venom Cask.
Twitch's Attack Speed is among the highest in the game; try purchasing items with on-hit effects such as Black Cleaver or Wit's End.
When Kayn is in terrain near you, you will get a visual warning on the edge of the terrain he's in.
Umbral Trespass requires Kayn to damage a target first. Try to dodge Blade's Reach to deny him a long range cast of Umbral Trespass.
Damage Kayn while he's in Shadow Step to shorten its duration, or apply hard crowd control (stun, charm, knockup, etc) to end Shadow Step immediately.
The stats provided here feature some vital Twitch versus Kayn matchup stats that can help you realize the distinctions between this set of champions. As an example, Twitch’s KDA ratio ([kills + assists] / deaths) of NaN is more than Kayn’s ratio of NaN, demonstrating that Twitch may be more central to his team's team fighting capacity than Kayn..
Twitch usually has a slightly larger longest kill spree than his enemy does. Commonly, he takes less damage than Kayn. This is usually reflective of different amounts of tankyness, but it can also imply that the one champ has less mobility and thus is not able to kite away from further damage when poked or engaged.
Both League champions are great champions. Both champs have their pros and cons. In the game's current meta, Twitch usually fairs equally well when trying to fight Kayn, with a 50.4% win rate. Therefore, Twitch makes an ok counter to Kayn.
While Twitch does have a higher win rate compared to Kayn, when on opposite teams, Twitch also has a lower level of difficulty that makes him a less time consuming character to learn and master. You still need to be cautious when picking Twitch into Kayn.
Moreover, Twitch also has only a small amount of CC and other utility, a similar amount to Kayn. This often makes her just as valuable during team fights, especially when facing champions with a ton of burst damage.
While there is not one best champion overall in League of Legends, in Twitch vs Kayn matchups, Twitch is the better champ with a similar win rate, less champion complexity, and a similar amount of utility to help out your team members during team fights.
Twitch is a decent counter for Kayn. Focus your tactics on keeping up your gold income and taking out objectives. If you can do that, you should be able to stand on your own as Twitch against Kayn.
To truly master Twitch to counter Kayn during both the laning and mid / late game phases of League of Legends, you should continue reading to pick up a few extra tips and tricks for this matchup. If you listen to the build and stats presented above, you will grow your win rate significantly and be that much closer to League of Legends pro players.
Twitch usually gets much more CS as Kayn. Champs who on average don't take much CS typically don't have to have much CS to be effective, such as support champions. These kinds of champions are capable of scaling well off of their abilities and first items alone. Yet, champions with a lot of CS, such as hyper-carries, often require a lot of items to be effective. In either case, try to do better than the numbers reported here to do well.
The most important items to use in your Twitch versus Kayn build consist of Runaan's Hurricane, Blade of The Ruined King, and The Collector. When Twitch combined at least these three pieces in his build, he performed significantly better against Kayn than with most other typical item sets. In fact, Twitch boasted an average win rate of 50.4% when countering Kayn with this counter build.
To have the best chance of coming out on top against Kayn as Twitch, you should equip the Hail of Blades, Taste of Blood, Eyeball Collection, Relentless Hunter, Presence of Mind, and Legend: Alacrity runes from the Domination and Precision rune sets. Out of all the rune builds players picked for Twitch vs Kayn clashes, this order of runes resulted in the best win rate. Notably, these runes averaged a 50.4% winrate overall.
If you want to see Twitch versus Kayn tips and counter stats for a a particular skill level, please choose one from the selection menu above. At first, the stats and strategies given are computed using all matches with data with both champions.