Contaminate has a large range; apply as many stacks of Deadly Venom as possible before using it.
You can catch up to an enemy out of attack range with Venom Cask.
Twitch's Attack Speed is among the highest in the game; try purchasing items with on-hit effects such as Black Cleaver or Wit's End.
Keep behind allied minions if Caitlyn is harassing you with Piltover Peacemaker (it deals less damage with each subsequent target).
You can intercept Ace in the Hole's missile from hitting an ally if you stand in its path.
The stats shown here show several important Twitch against Caitlyn matchup statistics that may help us figure out the differences and similarities between the two. For instance, Twitch’s KDA ratio ([kills + assists] / deaths) of NaN is more than Caitlyn’s ratio of NaN, highlighting that Twitch may be more central to his team's team fighting effectiveness than Caitlyn..
Twitch often has a slightly larger longest killing spree than his enemy does. On average, he receives a similar amount of damage to Caitlyn. This often reflects different amounts of tankyness, but it can also hint that the champ with increased HP has less mobility and thus is unable to escape additional damage when engaged or poked.
Both LoL champions are great champions. Both champs have their pros and cons. In the game's current meta, Twitch usually fairs equally well when facing off against Caitlyn, with a 50.8% win rate. As a result, Twitch makes an ok counter to Caitlyn.
While Twitch does have a higher winrate compared to Caitlyn, when they face off with one another, Twitch also has a greater level of difficulty that makes him a more complex champ to pick up and master. You still need to be cautious when picking Twitch into Caitlyn.
Furthermore, Twitch also has only a small amount of utility and CC, a similar amount to Caitlyn. This often makes her just as valuable during team fights, especially when trying to counter champions with a ton of burst damage.
While there isn't one best champion in League of Legends, in Twitch vs Caitlyn matchups, Twitch is the better champion with a similar win rate, similar champion depth, and a similar amount of utility to help out your allied champions during team fights.
Twitch is a decent counter to Caitlyn. Focus your actions on maximizing your CS and clearing objectives. If you are able to do that, you should be able to stand on your own as Twitch against Caitlyn.
If you would like to truly master Twitch to counter Caitlyn during both the lane and mid / late game phases of League of Legends, you should continue reading to pick up a few extra lessons on this matchup. If you mind the build and stats presented above, you should grow your win rate by a lot and be that much closer to League of Legends pro players.
Twitch typically gets a similar amount of CS as Caitlyn. Champions who typically don't acquire many minion kills typically don't need much CS to be effective, such as sup champs. These kinds of champions are able to scale well off of their skills, stats, and first items alone. Yet, champs with large amounts of CS, such as hyper-carries, often require several high cost items to be effective. In either situation, try to surpass the values reported on this page to do well.
The top items to have in your Twitch versus Caitlyn build include Infinity Edge, Bloodthirster, and Runaan's Hurricane. When Twitch incorporated at least these three pieces in his build, he did a lot better vs. Caitlyn than with most other typical counter builds. In fact, Twitch boasted an average winrate of 50.8% when countering Caitlyn with this build.
To have the highest likelihood of beating Caitlyn as Twitch, Twitch players should use the Hail of Blades, Sudden Impact, Eyeball Collection, Treasure Hunter, Future's Market, and Magical Footwear runes from the Domination and Inspiration rune sets. Out of all the runes players chose for Twitch vs Caitlyn counters, this sequence of runes yielded the best win rate. In fact, these runes averaged a 50.8% winrate overall.
If you need to see Twitch versus Caitlyn tips and matchup stats and build suggestions for a a specific player tier, please select one from the selection menu above. If viewing for the first time, the statistics and build suggestions given are calculated using all games run with these champs.