To maximize your ultimate's damage use it when there are many spheres on the battlefield.
After you hit an enemy champion with Force of Will follow up with Dark Sphere, they'll be slowed and have a hard time avoiding it.
Get one of your spells to rank 5 as quickly as possible, they gain powerful bonus effects at max rank.
Deny Vayne the opportunity to pin you against walls.
Vayne is fragile - turn the pressure up on her and she will be forced to play cautiously.
The stats shown here emphasize several important Syndra versus Vayne counter stats that may help us distinguish the distinctions between this set of champs. For instance, Syndra’s KDA ratio ([kills + assists] / deaths) of NaN is better than Vayne’s ratio of NaN, showing that Syndra may be more central to her team's team fighting effectiveness than Vayne..
Syndra normally has a similar longest kill spree as her counter does. Commonly, she receives less damage than Vayne. This commonly reflects different amounts of tankyness, yet it can also illustrate that the one champion has less agility and thus is not able to flee from additional damage when poked or engaged.
Both LoL champs are great. Both champs have their pros and cons. In League's current meta, Syndra usually fairs equally well when taking on Vayne, with a 49.9% win rate. As a result, Syndra makes an ok counter for Vayne.
While Syndra does have a lower winrate compared to Vayne, when facing one another, Syndra also has a greater level of difficulty that makes her a more challenging champ to pick up and master. You still need to be cautious when picking Syndra into Vayneas her relative depth means that you may not be able to unleash her full potential without a lot of practice beforehand.
Furthermore, Syndra also has a good amount of utility and CC, a similar amount to Vayne. This often makes her just as valuable during team fights, especially when trying to counter champions with a lot of burst damage.
While there isn't a single best champion for every situation in League of Legends, in Syndra vs Vayne matchups, Vayne is the better champ with a similar win rate, similar champion depth, and a similar amount of utility to help out your allies during late stage team fights.
Syndra is a somewhat poor counter to Vayne. You will do well by focussing your tactics on increasing your CS and destroying objectives. If you can do that, you should do very well as Syndra against Vayne.
To learn all of the intricacies of Syndra in order to counter Vayne during both the lane and mid / late game phases of League of Legends, you should keep reading to learn a few extra tricks and insights into this matchup. If you mind the build and tips displayed here, you will increase your win rate by a lot and be that much closer to League of Legends pro players.
Syndra often picks up a similar amount of CS relative to Vayne. Champs who on average don't earn many minion kills often don't require much CS to be valuable teammates, such as supports. They are able to scale properly off of their abilities and first items alone. Yet, champs with large amounts of CS, such as hyper-carries, typically require a lot of items to be effective. In either situation, try to exceed the values reported here to do well.
The top items to prioritize in your Syndra versus Vayne build include Rabadon's Deathcap, Zhonya's Hourglass, and Luden's Companion. When Syndra used at least these three items in her build, she did significantly better against Vayne than with most other typical builds. In fact, Syndra boasted an average winrate of 49.9% battling Vayne with this build.
To have the greatest probability of annihilating Vayne as Syndra, you should use the First Strike, Magical Footwear, Biscuit Delivery, Cosmic Insight, Manaflow Band, and Transcendence runes from the Inspiration and Sorcery rune sets. Out of all the rune sets that we analyzed for Syndra vs Vayne battles, this mixture of runes yielded the highest win rate. Moreover, these runes gave a 49.9% winrate overall.
By default, tips, statistics, and builds on how to beat Vayne as Syndra are presented for all skill levels combined. If you would like to narrow the statistics and builds to a particular player tier, you may use the selection menu at the top of this page.