Focus on dodging Wild Cards early when your champion doesn't have the hit points to afford getting hit.
If you have low Health, use Destiny as an indicator to run to safety. It will give you a head start in escaping any possible ganks.
The stats provided here underscore several significant Senna versus Twisted Fate matchup statistics that can help you figure out the differences and similarities between the two. As an example, Senna’s KDA ratio ([kills + assists] / deaths) of NaN is more than Twisted Fate’s KDA ratio of NaN, showing that Senna may be more central to her team's team fighting capability than Twisted Fate. This observation is in large part a result of the differences in assists.
Senna typically has a similar longest kill spree as her matchup does. Typically, she receives less damage than Twisted Fate. This is usually reflective of differing health capacities, but it can also illustrate that the champ with higher HP has less mobility and thus is unable to kite away from further damage when poked or engaged.
Both League of Legends champions are great. Both have their pros and cons. In the game's current meta, Senna usually fairs equally well when taking on Twisted Fate, with a 50.8% win rate. As a result, Senna makes an ok counter to Twisted Fate.
While Senna does have a higher win rate than Twisted Fate, when they face off with one another, Senna also has a lower learning curve that makes her a less complex champ to pick up and master. You should be careful when picking Senna into Twisted Fateas her relative depth means that you may not be able to unleash her full potential without a lot of practice beforehand.
Furthermore, Senna also has a good amount of CC and other utility, a similar amount to Twisted Fate. This often makes her just as valuable during team fights, especially when fighting champions with a ton of burst damage.
While there isn't a single best champion for every situation in League of Legends, in Senna vs Twisted Fate matchups, Senna is the better champ with a similar win rate, less champion complexity, and a similar amount of utility to help out your team members during late stage team fights.
Senna is a decent counter for Twisted Fate. You will do well by focussing your tactics on maximizing your gold income and clearing objectives. If you do that, you should do very well as Senna against Twisted Fate.
To truly master Senna in order to counter Twisted Fate during both the laning and mid / late game phases of League of Legends, you should continue reading to gather a few extra tips and tricks for this matchup. If you listen to the build and stats presented here, you will grow your win rate significantly and be that much closer to League of Legends pro players.
Senna typically accumulates less CS relative to Twisted Fate. Champions who on average don't acquire much CS typically don't have to have much CS to be effective, such as support champions. These kinds of champions are capable of scaling well off of their skills, stats, and first items alone. Yet, champions with a lot of CS, such as hyper-carries, usually have to have several high cost items to be effective. In either case, try to do better than the numbers reported on this page to do well.
The top items to use in your Senna versus Twisted Fate build include Youmuu's Ghostblade, Bloodsong, and Opportunity. When Senna bought at least these three pieces in her build, she performed significantly better versus Twisted Fate than with most other commonly used item sets. In fact, Senna boasted an average win rate of 50.8% when countering Twisted Fate with this counter build.
To have the greatest chance of defeating Twisted Fate as Senna, Senna players should take the Fleet Footwork, Presence of Mind, Legend: Alacrity, Cut Down, Biscuit Delivery, and Approach Velocity runes from the Precision and Inspiration rune sets. Of all the runes players picked for Senna vs Twisted Fate counter picks, this mixture of runes yielded the highest win rate. Notably, these runes gave a 50.8% win rate overall.
If you want to view Senna x Twisted Fate tips and counter builds for a an individual skill level, feel free to choose one from the selection menu shown above. At first, the stats and strategies displayed are computed using every match finished with both champions.