Nasus is prone to being kited. Try not to engage him at full Health.
Max rank Wither is a very effective counter to Attack Damage characters, so try to avoid getting caught alone by it.
While transformed by his ultimate, Nasus is stronger than most champions in the League. Engage him only if you have a clear advantage.
The stats shown on this page highlight some critical Senna vs. Nasus counter stats that may help us figure out the distinctions between the pair. Senna’s KDA ratio ([kills + assists] / deaths) of NaN is greater than Nasus’s ratio of NaN, highlighting that Senna may be more central to her team's team fighting effectiveness than Nasus. This observation is largely a result of the differences in assists.
Senna often has a similar longest killing spree as her opponent does. Typically, she takes less damage than Nasus. This often reflects differing health capacities, yet it can also show that the champion with more health has less agility and thus is unable to kite away from additional harm when poked or engaged.
Both League of Legends champs are great. Both have their pros and cons. In the game's current meta, Senna usually wins when taking on Nasus, with a 51.9% win rate. Therefore, Senna makes a good counter to Nasus.
While Senna does have a higher win rate than Nasus, when on opposite teams, Senna also has a greater level of difficulty that makes her a more complex champ to learn and master. You should be careful when picking Senna into Nasusas her relative depth means that you may not be able to unleash her full potential without a significant amount of practice beforehand.
Additionally, Senna has a good amount of CC and other utility, a similar amount to Nasus. This often makes her just as valuable during teamfights, especially when fighting champions with a lot of burst damage.
While there is not a single best champion overall in League of Legends, in Senna vs Nasus matchups, Senna is the better champion with a higher win rate, more champion depth, and a similar amount of utility to help out your team members during team fights.
Senna is a decent counter for Nasus. You will do well by focussing your play on maximizing your gold income and destroying objectives. If you do that, you should do very well as Senna against Nasus.
To truly master Senna in order to counter Nasus during both the laning and mid / late game phases of League of Legends, you should continue reading to pick up a few extra tips and tricks for this matchup. If you pay attention to the build and tips shown above, you will grow your win rate by a lot and be closer to League of Legends pro players.
Senna most often racks up less CS as Nasus. Champions who on average don't take many minion kills usualy don't have to have much CS to be effective, such as sup champs. They are able to scale well off of their abilities and first items alone. Yet, champions with large amounts of CS, such as hyper-carries, typically require several high cost items to be effective. In either situation, try to surpass the values reported here to do well.
The ideal items to use in your Senna versus Nasus build include Rapid Firecannon, Youmuu's Ghostblade, and Voltaic Cyclosword. When Senna bought at least these three pieces in her build, she did much better countering Nasus than with most other typical item sets. In fact, Senna boasted an average win rate of 51.9% when playing against Nasus with this counter build.
To have the greatest probability of coming out on top against Nasus as Senna, Senna players should take the Fleet Footwork, Presence of Mind, Legend: Alacrity, Cut Down, Bone Plating, and Revitalize runes from the Precision and Resolve rune sets. Of all the rune builds we have analyed for Senna vs Nasus clashes, this sequence of runes yielded the greatest win rate. Notably, these runes gave a 51.9% win rate overall.
If you would like to view Senna vs Nasus tips and counter stats for a an individual division rank, feel free to select one from the selection menu above. If viewing for the first time, the statistics and build suggestions displayed are computed using every round played with both champions.