Try to gank Anivia when she's laning. With multiple people, it is easier to ensure that her egg dies.
If you're playing a ranged champion, stay far enough away from Anivia so you can dodge Flash Frost more easily.
Try to fight Anivia in the lanes. In the jungle she can block pathways with lower ranks of Crystallize.
The stats shown on this page clarify several influential Senna against Anivia matchup statistics that can help you figure out the differences and similarities between this pair of champions. For instance, Senna’s KDA ratio ([kills + assists] / deaths) of NaN is better than Anivia’s KDA ratio of NaN, highlighting that Senna may be more central to her team's team fighting capacity than Anivia. This observation is in large part caused by the differences in assists.
Senna typically has a similar longest killing spree as her foe does. Typically, she takes less damage than Anivia. This often reflects differing health capacities, but it can also indicate that the champ with higher health has less mobility and thus is unable to escape additional damage when engaged or poked.
Both League champs are great champions. Both have their pros and cons. In League's current meta, Senna usually wins when taking on Anivia, with a 51.0% win rate. As a result, Senna makes a good counter for Anivia.
While Senna does have a higher win rate than Anivia, when on opposite teams, Senna also has a lower learning curve that makes her a less challenging character to develop with. You should be careful when picking Senna into Aniviaas her relative depth means that you may not be able to unleash her full potential without a significant amount of practice beforehand.
Moreover, Senna has a good amount of utility and CC, a similar amount to Anivia. This often makes her just as valuable during teamfights, especially when facing champions with a lot of burst damage.
While there isn't a single best champion for every situation in League of Legends, in Senna vs Anivia matchups, Senna is the better champion with a similar win rate, less champion complexity, and a similar amount of utility to help out your team members during teamfights.
Senna is a decent counter for Anivia. You will do well by focussing your play on increasing your gold income and clearing objectives. If you are able to do that, you should hold your own as Senna against Anivia.
If you would like to truly master Senna in order to counter Anivia during both the early game and mid / late game phases of League of Legends, you should keep reading to gather a few extra lessons on this matchup. If you listen to the build and stats displayed above, you should increase your win rate significantly and be closer to League of Legends pro players.
Senna often accumulates less CS compared to Anivia. Champions who on average don't get much CS often don't require much CS to be valuable teammates, such as sup champs. These kinds of champions are capable of scaling properly off of their abilities and first items alone. Yet, champions with large amounts of CS, such as hyper-carries, typically require several high cost items to be effective. In either case, try to exceed the numbers displayed on this page to do well.
The ideal items to focus on in your Senna versus Anivia build include Rapid Firecannon, Bloodsong, and Voltaic Cyclosword. When Senna bought at least these three pieces in her build, she performed significantly better when fighting Anivia than with many other common builds. In fact, Senna had an average win rate of 51.0% battling Anivia with this counter build.
To have the best probability of vanquishing Anivia as Senna, you should equip the Fleet Footwork, Presence of Mind, Legend: Alacrity, Cut Down, Biscuit Delivery, and Approach Velocity runes from the Precision and Inspiration rune sets. Out of all the rune sets players chose for Senna vs Anivia battles, this order of runes resulted in the highest win rate. Moreover, these runes averaged a 51.0% winrate overall.
If you would like to view Senna vs Anivia tips and counter stats for a a particular division rank, feel free to choose one from the selection menu displayed above. By default, the stats and build suggestions given are calculated using every game played with both champs.