Focus on dodging Wild Cards early when your champion doesn't have the hit points to afford getting hit.
If you have low Health, use Destiny as an indicator to run to safety. It will give you a head start in escaping any possible ganks.
The stat comparisons provided here show several influential Samira vs. Twisted Fate counter statistics that can help us explain the differences between the pair. Samira’s KDA ratio ([kills + assists] / deaths) of NaN is greater than Twisted Fate’s ratio of NaN, demonstrating that Samira may be more central to her team's team fighting potential than Twisted Fate. This observation is largely fueled by the difference in kills.
Samira usually has a slightly larger longest kill spree than her opponent does. Typically, she receives a similar amount of damage to Twisted Fate. This often reflects different amounts of tankyness, but it can also indicate that the one champion has less agility and thus is unable to kite away from further harm when engaged or poked.
Both League of Legends champs are great. Both champs have their pros and cons. In the game's current meta, Samira usually fairs equally well when trying to fight Twisted Fate, with a 49.8% win rate. Thus, Samira makes an ok counter for Twisted Fate.
While Samira does have a lower winrate compared to Twisted Fate, when on opposite teams, Samira also has a lower level of difficulty that makes her a less time consuming champ to learn and master. You should be careful when picking Samira into Twisted Fate.
Moreover, Samira also has almost no amount of CC and other utility, a similar amount to Twisted Fate. This often makes her just as valuable during teamfights, especially when facing champions with a ton of burst damage.
While there isn't one best champion in League of Legends, in Samira vs Twisted Fate matchups, Twisted Fate is the better champion with a similar win rate, less champion complexity, and a similar amount of utility to help out your teammates during teamfights.
Samira is a somewhat poor counter to Twisted Fate. You will do well by focussing your actions on keeping up your gold income and taking out objectives. If you are able to do that, you should be able to stand on your own as Samira against Twisted Fate.
If you would like to learn all of the intricacies of Samira to counter Twisted Fate during both the early game and mid / late game phases of League of Legends, you should continue reading to learn a few extra lessons on this matchup. If you pay attention to the build and tips shown above, you will increase your win rate by a lot and be closer to League of Legends pro players.
Samira often gets a similar amount of CS compared to Twisted Fate. Champs who typically don't acquire many minion kills often don't need much CS to be valuable teammates, such as support champions. They are capable of scaling well off of their skills, stats, and first items alone. Yet, champs with large amounts of CS, such as hyper-carries, typically need many items to be effective. In either case, try to surpass the values shown on this page to do well.
The most important items to focus on in your Samira versus Twisted Fate build consist of Guardian Angel, Immortal Shieldbow, and The Collector. When Samira incorporated at least these three items in her build, she did a lot better against Twisted Fate than with most other typical counter builds. In fact, Samira boasted an average win rate of 49.8% battling Twisted Fate with these items in her kit.
To have the highest probability of annihilating Twisted Fate as Samira, you should use the Conqueror, Triumph, Legend: Bloodline, Last Stand, Sudden Impact, and Treasure Hunter runes from the Precision and Domination rune sets. Out of all the runes players picked for Samira vs Twisted Fate fights, this combination of runes resulted in the highest win rate. Moreover, these runes averaged a 49.8% winrate overall.
If you want to view Samira versus Twisted Fate tips and builds for a a particular rank, feel free to choose one from the selection menu shown above. By default, the statistics and guides given are calculated using all rounds played with these champs.