Spell Flux's short cooldown allows it to be used to spread Flux to many enemies.
Use Overload's passive to optimize for maximum damage or maximum speed.
Ryze can move and cast other spells while Realm Warp is charging without cancelling the portal.
Karthus can cast spells for a short duration after he is killed. Move away from his corpse to be safe.
Make sure you always have enough health to survive Requiem, even if you have to go back to the base more frequently to heal.
The stats shown here show some important Ryze against Karthus counter statistics that can help you explain the differences between this pair of champions. Ryze’s KDA ratio ([kills + assists] / deaths) of NaN is greater than Karthus’s ratio of NaN, showing that Ryze may be more central to his team's team fighting capability than Karthus..
Ryze typically has a similar longest killing spree as his foe does. On average, he receives a similar amount of damage to Karthus. This commonly reflects different amounts of tankyness; however, it can also show that the champ with higher health has less agility and thus is not able to kite away from further damage when engaged or poked.
Both LoL champions are great. Both champs have their pros and cons. In the game's current meta, Ryze usually wins when taking on Karthus, with a 53.4% win rate. Thus, Ryze makes a great counter for Karthus.
While Ryze does have a higher win rate than Karthus, when facing one another, Ryze also has a greater level of difficulty that makes him a more time consuming champ to pick up and master. You should be be fine when picking Ryze into Karthusas his relative depth means that you may not be able to reach his full potential without a significant amount of practice beforehand.
Additionally, Ryze has some amount of CC and other utility, a similar amount to Karthus. This makes her just as valuable during teamfights, especially when fighting champions with a lot of burst damage.
While there is not one best champion for every situation in League of Legends, in Ryze vs Karthus matchups, Ryze is the better champ with a noticably higher win rate, similar champion depth, and a similar amount of utility to help out your allied champions during team fights.
Ryze is a great counter to Karthus. Focus your tactics on keeping up your gold income and clearing objectives. If you do that, you should hold your own as Ryze against Karthus.
If you would like to truly master Ryze to counter Karthus during both the early game and mid / late game phases of League of Legends, you should continue reading to learn a few extra tips and tricks for this matchup. If you pay attention to the build and suggestions presented here, you will increase your win rate by a lot and be that much closer to League of Legends pro players.
Ryze often racks up more CS compared to Karthus. Champs who on average don't earn many minion kills often don't have to have much CS to be valuable teammates, such as sup champs. They are capable of scaling well off of their abilities and first items alone. Yet, champs with large amounts of CS, such as hyper-carries, often have to have a lot of items to be effective. In either situation, try to do better than the numbers displayed here to do well.
The most crucial items to use in your Ryze versus Karthus build include Seraph's Embrace, Rabadon's Deathcap, and Rod of Ages. When Ryze combined at least these three pieces in his build, he performed significantly better against Karthus than with most other commonly used item sets. In fact, Ryze had an average win rate of 53.4% battling Karthus with this counter build.
To have the best likelihood of vanquishing Karthus as Ryze, you should use the Phase Rush, Manaflow Band, Transcendence, Gathering Storm, Bone Plating, and Overgrowth runes from the Sorcery and Resolve rune sets. Of all the rune combinations that we analyzed for Ryze vs Karthus counter picks, this order of runes yielded the highest win rate. Notably, these runes provided a 53.4% winrate overall.
If you would like to see Ryze versus Karthus tips and matchup stats and build suggestions for a a specific player tier, feel free to select one from the selection menu above. By default, the statistics and build suggestions shown are calculated using every match played with these champs.