Mortal Will activates after 5 spells or basic attacks - plan your way through fights to allow you to activate it more than once.
Whittle the enemy down with Comet Spears before you jump in.
If an enemy is going to get out of range of your Aegis Assault, you can recast the spell to immediately fire the shield slam.
Deny Vayne the opportunity to pin you against walls.
Vayne is fragile - turn the pressure up on her and she will be forced to play cautiously.
The stats provided here emphasize some vital Pantheon versus Vayne counter stats that may help you understand the differences and similarities between the two. Pantheon’s KDA ratio ([kills + assists] / deaths) of NaN is greater than Vayne’s ratio of NaN, showing that Pantheon may be more central to his team's team fighting effectiveness than Vayne..
Pantheon normally has a similar longest kill spree as his opponent does. Typically, he receives more damage than Vayne. This is usually reflective of differing health capacities; however, it can also show that the one champ has less agility and thus is unable to flee from additional damage when engaged or poked.
Both LoL champs are great. Both champs have their strengths, weaknesses, and counters. In the game's current meta, Pantheon usually fairs equally well when playing against Vayne, with a 49.5% win rate. Therefore, Pantheon makes an ok counter for Vayne.
While Pantheon does have a lower win rate than Vayne, when facing one another, Pantheon also has a much lower level of difficulty that makes him a less challenging champ to learn and master. You should be careful when picking Pantheon into Vayne.
Furthermore, Pantheon has some amount of CC and other utility, a similar amount to Vayne. This often makes her just as valuable during team fights, especially when facing champions with a lot of burst damage.
While there is not one best champion for every situation in League of Legends, in Pantheon vs Vayne matchups, Vayne is the better champion with a similar win rate, less champion complexity, and a similar amount of utility to help out your teammates during late stage team fights.
Pantheon is a somewhat poor counter for Vayne. Make sure you focus your strategy on maximizing your CS and taking out objectives. If you do that, you should be able to stand on your own as Pantheon against Vayne.
To truly master Pantheon in order to counter Vayne during both the laning and mid / late game phases of League of Legends, you should continue reading to gather a few extra lessons on this matchup. If you pay attention to the build and stats shown above, you will grow your win rate significantly and be closer to League of Legends pro players.
Pantheon typically picks up less CS as Vayne. Champions who on average don't take many minion kills often don't require much CS to be valuable teammates, such as supports. They are capable of scaling properly off of their skills, stats, and first items alone. Yet, champs with large amounts of CS, such as hyper-carries, usually have to have many items to be effective. In either situation, try to do better than the numbers shown here to do well.
The best items to prioritize in your Pantheon versus Vayne build include Black Cleaver, Blade of The Ruined King, and Eclipse. When Pantheon incorporated at least these three items in his build, he did significantly better vs. Vayne than with many other commonly used counter builds. In fact, Pantheon had an average winrate of 49.5% when playing against Vayne with this counter build.
To have the highest likelihood of crushing Vayne as Pantheon, you should use the Press the Attack, Presence of Mind, Legend: Tenacity, Last Stand, Transcendence, and Scorch runes from the Precision and Sorcery rune sets. Of all the rune builds players chose for Pantheon vs Vayne counterpicks, this composite of runes resulted in the best win rate. Notably, these runes averaged a 49.5% win rate overall.
By default, tips, stats, and builds on how to beat Vayne as Pantheon are given for all ranked divisions. If you would like to filter the stats and builds to a particular rank, you can use the selection menu above.