Mortal Will activates after 5 spells or basic attacks - plan your way through fights to allow you to activate it more than once.
Whittle the enemy down with Comet Spears before you jump in.
If an enemy is going to get out of range of your Aegis Assault, you can recast the spell to immediately fire the shield slam.
Karthus can cast spells for a short duration after he is killed. Move away from his corpse to be safe.
Make sure you always have enough health to survive Requiem, even if you have to go back to the base more frequently to heal.
The stat comparisons shown here highlight some vital Pantheon vs. Karthus counter stats that can help us explain the distinctions between the two. Pantheon’s KDA ratio ([kills + assists] / deaths) of NaN is greater than Karthus’s ratio of NaN, indicating that Pantheon may be more central to his team's team fighting capability than Karthus..
Pantheon normally has a similar longest killing spree as his enemy does. On average, he takes a similar amount of damage to Karthus. This is usually reflective of different amounts of tankyness, but it can also show that the one champ has less mobility and thus is unable to kite away from further harm when engaged or poked.
Both LoL champions are great champions. Both champs have their pros and cons. In League's current meta, Pantheon usually wins when taking on Karthus, with a 51.4% win rate. Thus, Pantheon makes a good counter for Karthus.
While Pantheon does have a higher win rate than Karthus, when on opposite teams, Pantheon also has a lower difficulty level that makes him a less time consuming character to develop with. You should be careful when picking Pantheon into Karthus.
Additionally, Pantheon has some amount of CC and other utility, a similar amount to Karthus. This makes her just as valuable during team fights, especially when facing champions with a ton of burst damage.
While there isn't one best champion for every situation in League of Legends, in Pantheon vs Karthus matchups, Pantheon is the better champion with a higher win rate, less champion complexity, and a similar amount of utility to help out your allied champions during late stage team fights.
Pantheon is a decent counter for Karthus. You will do well by focussing your strategy on keeping up your gold and cs and taking out objectives. If you do that, you should do very well as Pantheon against Karthus.
To truly master Pantheon to counter Karthus during both the lane and mid / late game phases of League of Legends, you should keep reading to learn a few extra tricks and insights into this matchup. If you listen to the build and tips shown above, you will grow your win rate by a lot and be that much closer to League of Legends pro players.
Pantheon usually accumulates a similar amount of CS compared to Karthus. Champions who typically don't acquire much CS usualy don't have to have much CS to be effective, such as sup champs. They are capable of scaling properly off of their skills, stats, and first items alone. Yet, champions with large amounts of CS, such as hyper-carries, typically require several high cost items to be effective. In either case, try to exceed the numbers shown on this page to do well.
The most crucial items to prioritize in your Pantheon versus Karthus build include Maw of Malmortius, Spear of Shojin, and Eclipse. When Pantheon used at least these three items in his build, he performed significantly better versus Karthus than with many other commonly used counter builds. In fact, Pantheon had an average win rate of 51.4% battling Karthus with this build.
To have the greatest chance of beating Karthus as Pantheon, Pantheon players should use the Press the Attack, Triumph, Legend: Tenacity, Coup de Grace, Sudden Impact, and Treasure Hunter runes from the Precision and Domination rune sets. Of all the runes players chose for Pantheon vs Karthus counters, this blending of runes yielded the highest win rate. In fact, these runes averaged a 51.4% win rate overall.
If you want to see Pantheon x Karthus tips and counter builds for a a specific player tier, please choose one from the selection menu displayed above. By default, the stats and strategies given are calculated using all matches completed with both champs.