You can set her passive to use hotkeys in the options menu. The default is Shift+F1~F5
Try to use Inherent Glamour sparingly, ineffective uses will put enemies on the alert.
Get boots early when playing against Syndra, they'll help you avoid many of her spells.
Attack Syndra after she's used Scatter the Weak, it has a long cooldown so she'll be vulnerable.
At max rank Syndra's spells gain bonus effects and change in appearance.
The stats provided here emphasize several vital Neeko against Syndra matchup statistics that may help us distinguish the differences and similarities between these two champs. Neeko’s KDA ratio ([kills + assists] / deaths) of NaN is better than Syndra’s KDA ratio of NaN, indicating that Neeko may be more central to her team's team fighting effectiveness than Syndra..
Neeko normally has a slightly smaller longest kill spree than her enemy does. Commonly, she takes a similar amount of damage to Syndra. This commonly reflects differing health capacities; however, it can also show that the champion with higher HP has less mobility and thus is not able to kite away from additional damage when poked or engaged.
Both League champions are great. Both champs have their strengths, weaknesses, and counters. In League's current meta, Neeko usually fairs equally well when playing against Syndra, with a 49.4% win rate. As a result, Neeko makes an ok counter for Syndra.
While Neeko does have a lower win rate than Syndra, when on opposite teams, Neeko also has a lower level of difficulty that makes her a less difficult champ to pick up and master. You still need to be cautious when picking Neeko into Syndra.
Additionally, Neeko has some amount of CC and other utility, a similar amount to Syndra. This often makes her just as valuable during teamfights, especially when facing champions with a lot of burst damage.
While there is not a single best champion overall in League of Legends, in Neeko vs Syndra matchups, Syndra is the better champ with a similar win rate, less champion complexity, and a similar amount of utility to help out your teammates during team fights.
Neeko is a somewhat poor counter to Syndra. You will do well by focussing your actions on maximizing your CS and clearing objectives. If you can do that, you should be able to stand on your own as Neeko against Syndra.
To learn all of the intricacies of Neeko to counter Syndra during both the early game and mid / late game phases of League of Legends, you should keep reading to learn a few extra lessons on this matchup. If you mind the build and stats shown above, you will grow your win rate significantly and be that much closer to League of Legends pro players.
Neeko most often accumulates less CS relative to Syndra. Champs who on average don't get much CS usualy don't need much CS to be effective, such as sup champs. These kinds of champions are able to scale well off of their skills, stats, and first items alone. Yet, champs with a lot of CS, such as hyper-carries, typically need many items to be effective. In either situation, try to surpass the values reported here to do well.
The top items to use in your Neeko versus Syndra build consist of Rabadon's Deathcap, Hextech Rocketbelt, and Stormsurge. When Neeko bought at least these three pieces in her build, she performed much better versus Syndra than with many other common builds. In fact, Neeko had an average win rate of 49.4% when playing against Syndra with this build.
To have the greatest chance of vanquishing Syndra as Neeko, you should take the Arcane Comet, Manaflow Band, Transcendence, Scorch, Cheap Shot, and Ultimate Hunter runes from the Sorcery and Domination rune sets. Of all the rune combinations players used for Neeko vs Syndra fights, this mixture of runes yielded the best win rate. Notably, these runes provided a 49.4% winrate overall.
By default, tips, stats, and builds on how to beat Syndra as Neeko are given for all skill levels, merged. If you want to filter the stats and builds to a particular player tier, you can use the selection menu above.