You can set her passive to use hotkeys in the options menu. The default is Shift+F1~F5
Try to use Inherent Glamour sparingly, ineffective uses will put enemies on the alert.
The stats shown here highlight several influential Neeko versus Senna counter stats that may help you grasp the differences between the pair. Neeko’s KDA ratio ([kills + assists] / deaths) of NaN is better than Senna’s ratio of NaN, indicating that Neeko may be more central to her team's team fighting capacity than Senna..
Neeko typically has a similar longest killing spree as her counter does. Typically, she takes a similar amount of damage to Senna. This often reflects different amounts of tankyness, but it can also imply that the champion with more HP has less mobility and thus is unable to kite away from further damage when engaged or poked.
Both League champs are great champions. Both champs have their strengths, weaknesses, and counters. In the game's current meta, Neeko usually fairs equally well when playing against Senna, with a 49.5% win rate. Therefore, Neeko makes an ok counter to Senna.
While Neeko does have a lower win rate than Senna, when facing one another, Neeko also has a lower learning curve that makes her a less complex champ to learn and master. You should be careful when picking Neeko into Senna.
Moreover, Neeko has some amount of utility and CC, a similar amount to Senna. This makes her just as valuable during teamfights, especially when facing champions with a lot of burst damage.
While there is not one best champion overall in League of Legends, in Neeko vs Senna matchups, Senna is the better champion with a similar win rate, less champion complexity, and a similar amount of utility to help out your team members during teamfights.
Neeko is a somewhat poor counter to Senna. Make sure you focus your gameplay on increasing your gold income and taking out objectives. If you are able to do that, you should be able to stand on your own as Neeko against Senna.
If you would like to truly master Neeko in order to counter Senna during both the laning and mid / late game phases of League of Legends, you should continue reading to pick up a few extra tricks and insights into this matchup. If you listen to the build and suggestions shown above, you will grow your win rate by a lot and be that much closer to League of Legends pro players.
Neeko often gets more CS relative to Senna. Champs who typically don't take many minion kills typically don't need much CS to be effective, such as sup champs. These kinds of champions are able to scale well off of their abilities and first items alone. Yet, champs with a lot of CS, such as hyper-carries, usually require several high cost items to be effective. In either situation, try to exceed the numbers shown on this page to do well.
The ideal items to use in your Neeko versus Senna build include Rabadon's Deathcap, Zaz'Zak's Realmspike, and Stormsurge. When Neeko incorporated at least these three items in her build, she performed a lot better versus Senna than with most other typical counter builds. In fact, Neeko boasted an average winrate of 49.5% battling Senna with these items in her kit.
To have the best likelihood of defeating Senna as Neeko, Neeko players should equip the Arcane Comet, Manaflow Band, Transcendence, Scorch, Biscuit Delivery, and Cosmic Insight runes from the Sorcery and Inspiration rune sets. Of all the rune combinations players chose for Neeko vs Senna counters, this combination of runes yielded the highest win rate. In fact, these runes provided a 49.5% winrate overall.
If you want to get Neeko versus Senna tips and builds for a a particular division, feel free to choose one from the selection menu provided above. By default, the statistics and strategies given are calculated using every round finished with both champions.