You can set her passive to use hotkeys in the options menu. The default is Shift+F1~F5
Try to use Inherent Glamour sparingly, ineffective uses will put enemies on the alert.
Be wary of Cassiopeia's damage potential with Twin Fang when she has you poisoned.
Turn away from Cassiopeia when she is casting Petrifying Gaze to get slowed instead of stunned.
The stats shown on this page underscore some valuable Neeko versus Cassiopeia counter statistics that can help you interpret the differences and similarities between this set of champions. For instance, Neeko’s KDA ratio ([kills + assists] / deaths) of NaN is more than Cassiopeia’s ratio of NaN, indicating that Neeko may be more central to her team's team fighting capability than Cassiopeia..
Neeko usually has a slightly smaller longest kill spree than her opponent does. On average, she receives less damage than Cassiopeia. This commonly reflects different amounts of tankyness, but it can also imply that the one champ has less agility and thus is not able to flee from further harm when engaged or poked.
Both League of Legends champs are great champions. Both have their strengths, weaknesses, and counters. In the game's current meta, Neeko usually fairs equally well when playing against Cassiopeia, with a 50.8% win rate. As a result, Neeko makes an ok counter to Cassiopeia.
While Neeko does have a higher win rate than Cassiopeia, when they face off with one another, Neeko also has a much lower level of difficulty that makes her a less complex champion to pick up and master. You should be careful when picking Neeko into Cassiopeia.
Moreover, Neeko also has some amount of CC and other utility, a similar amount to Cassiopeia. This makes her just as valuable during team fights, especially when facing champions with a ton of burst damage.
While there isn't a single best champion overall in League of Legends, in Neeko vs Cassiopeia matchups, Neeko is the better champion with a similar win rate, less champion complexity, and a similar amount of utility to help out your teammates during teamfights.
Neeko is a decent counter for Cassiopeia. You will do well by focussing your gameplay on keeping up your CS and taking out objectives. If you do that, you should be able to stand on your own as Neeko against Cassiopeia.
To learn all of the intricacies of Neeko to counter Cassiopeia during both the laning and mid / late game phases of League of Legends, you should keep reading to pick up a few extra tricks and insights into this matchup. If you pay attention to the build and suggestions presented here, you will increase your win rate significantly and be closer to League of Legends pro players.
Neeko often racks up less CS relative to Cassiopeia. Champions who typically don't take many minion kills usualy don't require much CS to be effective, such as supports. These kinds of champions are able to scale well off of their skills, stats, and first items alone. Yet, champs with a lot of CS, such as hyper-carries, often need many items to be effective. In either situation, try to exceed the values reported here to do well.
The most important items to prioritize in your Neeko versus Cassiopeia build include Hextech Rocketbelt, Shadowflame, and Stormsurge. When Neeko included at least these three items in her build, she did significantly better countering Cassiopeia than with most other commonly used counter builds. In fact, Neeko boasted an average winrate of 50.8% battling Cassiopeia with these items in her kit.
To have the best probability of beating Cassiopeia as Neeko, you should use the Arcane Comet, Manaflow Band, Transcendence, Scorch, Biscuit Delivery, and Cosmic Insight runes from the Sorcery and Inspiration rune sets. Out of all the rune sets we have analyed for Neeko vs Cassiopeia clashes, this blending of runes yielded the greatest win rate. Moreover, these runes gave a 50.8% winrate overall.
If you want to view Neeko x Cassiopeia tips and builds for a an individual player tier, feel free to choose one from the selection menu shown above. By default, the statistics and guides given are calculated using every match run with these champions.