Kassadin's ultimate has many uses and is on a shorter cooldown than most, use it often.
Kassadin has multiple item paths; he can go caster via Mana and Ability Power or anti-caster with Cooldown Reduction and Magic Resist.
Try to get the Ancient Golem buff to counteract Riftwalk's increasing Mana cost.
The stats shown here highlight several vital Kassadin versus Qiyana matchup stats that may help you appreciate the differences and similarities between the pair. As an example, Kassadin’s KDA ratio ([kills + assists] / deaths) of NaN is greater than Qiyana’s KDA ratio of NaN, demonstrating that Kassadin may be more central to his team's team fighting capacity than Qiyana..
Kassadin usually has a slightly smaller longest killing spree than his foe does. On average, he receives more damage than Qiyana. This commonly reflects different amounts of tankyness; however, it can also show that the champ with higher HP has less agility and thus is not able to flee from further damage when poked or engaged.
Both LoL champions are great champions. Both champs have their pros and cons. In the game's current meta, Kassadin usually fairs equally well when playing against Qiyana, with a 49.5% win rate. Thus, Kassadin makes an ok counter to Qiyana.
While Kassadin does have a lower winrate compared to Qiyana, when on opposite teams, Kassadin also has a greater difficulty level that makes him a more difficult champ to learn and master. You should be careful when picking Kassadin into Qiyanaas his relative depth means that you may not be able to reach his full potential without a lot of practice beforehand.
Additionally, Kassadin also has some amount of utility and CC, a similar amount to Qiyana. This makes her just as valuable during teamfights, especially when trying to counter champions with a lot of burst damage.
While there is not a single best champion overall in League of Legends, in Kassadin vs Qiyana matchups, Qiyana is the better champion with a similar win rate, similar champion depth, and a similar amount of utility to help out your allied champions during late stage team fights.
Kassadin is a somewhat poor counter to Qiyana. Focus your play on maximizing your gold and cs and taking out objectives. If you do that, you should be able to stand on your own as Kassadin against Qiyana.
If you would like to learn all of the intricacies of Kassadin in order to counter Qiyana during both the lane and mid / late game phases of League of Legends, you should keep reading to pick up a few extra tricks and insights into this matchup. If you mind the build and stats displayed above, you should increase your win rate by a lot and be closer to League of Legends pro players.
Kassadin most often racks up a similar amount of CS relative to Qiyana. Champs who on average don't take many minion kills often don't need much CS to be valuable teammates, such as supports. They are capable of scaling properly off of their skills, stats, and first items alone. Yet, champions with large amounts of CS, such as hyper-carries, often have to have several high cost items to be effective. In either case, try to do better than the numbers reported here to do well.
The best items to focus on in your Kassadin versus Qiyana build include Seraph's Embrace, Malignance, and Zhonya's Hourglass. When Kassadin included at least these three pieces in his build, he did much better countering Qiyana than with most other common builds. In fact, Kassadin had an average win rate of 49.5% when playing against Qiyana with these items in his kit.
To have the greatest probability of defeating Qiyana as Kassadin, you should equip the First Strike, Magical Footwear, Future's Market, Cosmic Insight, Sudden Impact, and Ultimate Hunter runes from the Inspiration and Domination rune sets. Out of all the rune sets players used for Kassadin vs Qiyana fights, this combo of runes resulted in the best win rate. In fact, these runes provided a 49.5% win rate overall.
If you need to see Kassadin vs Qiyana tips and counter stats for a a distinct division, feel free to choose one from the selection menu shown above. At first, the stats and guides given are calculated using all matches completed with these champions.