Lay Waste is very strong at farming minions and harassing enemy champions.
Ask your allies to help point out when you should use Requiem to get kills in different lanes.
Moving closer to Zyra can be a smart move if she places plants too far away from herself.
Moving the fight to a different area will deprive Zyra of accumulated seeds.
Plants take fixed damage from attacks and effects, similar to wards. They also expire quickly on their own.
Seeds placed by Zyra's W are larger, a different color, and grant a small amount of vision to her team.
Zyra's seeds can be destroyed by stepping on them. If she tries to grow them as you do, dodge back at the last moment.
The stats shown here feature several influential Karthus vs. Zyra matchup stats that may help you interpret the differences between this set of champs. For instance, Karthus’s KDA ratio ([kills + assists] / deaths) of NaN is greater than Zyra’s KDA ratio of NaN, demonstrating that Karthus may be more central to his team's team fighting effectiveness than Zyra. This observation is largely caused by the difference in kills.
Karthus usually has a much larger longest killing spree than his enemy does. On average, he takes more damage than Zyra. This often reflects differing health capacities, but it can also imply that the champion with higher health has less agility and thus is unable to kite away from further harm when poked or engaged.
Both League champs are great. Both have their strengths, weaknesses, and counters. In League's current meta, Karthus usually loses when taking on Zyra, with a 45.7% win rate. Thus, Karthus makes a poor counter to Zyra.
While Karthus does have a much lower win rate than Zyra, when they face off with one another, Karthus also has a greater learning curve that makes him a more challenging champion to learn and master. You should be very concerned when picking Karthus into Zyraas his relative depth means you may not be able to unleash his full potential without a significant amount of practice beforehand.
Furthermore, Karthus also has some amount of CC and other utility, a similar amount to Zyra. This often makes her just as valuable during team fights, especially when fighting champions with a ton of burst damage.
While there isn't a single best champion overall in League of Legends, in Karthus vs Zyra matchups, Zyra is the better champion with a much lower win rate, similar champion depth, and a similar amount of utility to help out your teammates during late stage team fights.
Karthus is a bad counter to Zyra. Focus your play on keeping up your gold income and taking out objectives. If you can do that, you should be able to stand on your own as Karthus against Zyra.
To learn all of the intricacies of Karthus to counter Zyra during both the early game and mid / late game phases of League of Legends, you should keep reading to pick up a few extra lessons on this matchup. If you pay attention to the build and tips shown above, you will grow your win rate by a lot and be closer to League of Legends pro players.
Karthus usually picks up more CS relative to Zyra. Champions who on average don't acquire many minion kills typically don't have to have much CS to be effective, such as sup champs. They are able to scale properly off of their skills, stats, and first items alone. Yet, champions with a lot of CS, such as hyper-carries, typically need several high cost items to be effective. In either situation, try to surpass the values displayed on this page to do well.
The most important items to focus on in your Karthus versus Zyra build include Rabadon's Deathcap, Stormsurge, and Liandry's Torment. When Karthus combined at least these three items in his build, he performed a lot better versus Zyra than with many other typical builds. In fact, Karthus boasted an average win rate of 45.7% when countering Zyra with this counter build.
To have the best probability of beating Zyra as Karthus, you should take the First Strike, Magical Footwear, Future's Market, Cosmic Insight, Eyeball Collection, and Ultimate Hunter runes from the Inspiration and Domination rune sets. Of all the rune sets that we analyzed for Karthus vs Zyra counter picks, this combo of runes yielded the greatest win rate. Notably, these runes provided a 45.7% win rate overall.
By default, tips, statistics, and builds on how to beat Zyra as Karthus are given for every ranked division. To narrow the statistics and builds to a specific division, you can use the selection menu earlier in the counter matchup guide.