Lay Waste is very strong at farming minions and harassing enemy champions.
Ask your allies to help point out when you should use Requiem to get kills in different lanes.
Zoe's Paddle Star deals more damage the further it has flown.
Sleepy Trouble Bubble travels further over walls. Stop Zoe from hiding in fog of war to prevent her from setting the spell up.
Zoe must return to her starting point after casting Portal Jump, making her vulnerable to a counterattack.
The stat comparisons shown here emphasize several significant Karthus vs. Zoe matchup statistics that may help you appreciate the distinctions between the two. As an example, Karthus’s KDA ratio ([kills + assists] / deaths) of NaN is greater than Zoe’s ratio of NaN, indicating that Karthus may be more central to his team's team fighting potential than Zoe..
Karthus typically has a similar longest kill spree as his matchup does. Commonly, he receives more damage than Zoe. This typically indicates differing health capacities; however, it can also illustrate that the champion with increased HP has less agility and thus is unable to escape further damage when engaged or poked.
Both League champs are great champions. Both have their strengths, weaknesses, and counters. In the game's current meta, Karthus usually wins when facing off against Zoe, with a 51.9% win rate. Thus, Karthus makes a good counter to Zoe.
While Karthus does have a higher winrate compared to Zoe, when facing one another, Karthus also has a greater learning curve that makes him a more challenging champion to develop with. You should be careful when picking Karthus into Zoeas his relative depth means you may not be able to unleash his full potential without a significant amount of practice beforehand.
Additionally, Karthus has some amount of CC and other utility, a similar amount to Zoe. This makes her just as valuable during team fights, especially when fighting champions with a lot of burst damage.
While there is not a single best champion in League of Legends, in Karthus vs Zoe matchups, Karthus is the better champion with a higher win rate, more champion depth, and a similar amount of utility to help out your teammates during teamfights.
Karthus is a decent counter for Zoe. Focus your gameplay on keeping up your gold income and taking out objectives. If you do that, you should hold your own as Karthus against Zoe.
To truly master Karthus in order to counter Zoe during both the laning and mid / late game phases of League of Legends, you should continue reading to gather a few extra tricks and insights into this matchup. If you pay attention to the build and stats displayed here, you will grow your win rate significantly and be closer to League of Legends pro players.
Karthus typically racks up less CS relative to Zoe. Champions who typically don't take much CS usualy don't have to have much CS to be effective, such as supports. They are capable of scaling properly off of their abilities and first items alone. Yet, champions with a lot of CS, such as hyper-carries, often need many items to be effective. In either case, try to surpass the values shown here to do well.
The most crucial items to have in your Karthus versus Zoe build include Rabadon's Deathcap, Shadowflame, and Liandry's Torment. When Karthus combined at least these three items in his build, he performed a lot better when facing Zoe than with many other common builds. In fact, Karthus had an average win rate of 51.9% when playing against Zoe with these items in his kit.
To have the best likelihood of vanquishing Zoe as Karthus, you should take the First Strike, Magical Footwear, Future's Market, Cosmic Insight, Eyeball Collection, and Ultimate Hunter runes from the Inspiration and Domination rune sets. Out of all the rune sets that we analyzed for Karthus vs Zoe counter picks, this set of runes resulted in the highest win rate. Moreover, these runes provided a 51.9% winrate overall.
If you need to view Karthus vs Zoe tips and matchup stats and build suggestions for a a particular division rank, please select one from the selection menu displayed above. By default, the stats and guides shown are computed using every game with data with these champions.