Karthus vs Vayne
How to Beat Vayne as Karthus
based on 2,610 Karthus vs Vayne matchupsHow We Analyze LoL Champion Counters
Karthus vs Vayne Matchup Summary
Best Karthus vs Vayne Counter Build
Items
Starter Items
Early Items
Core Karthus Items
Optional Items
Summoner Spells
Skill Order
Runes
Guide to Countering Vayne as Karthus
Tips for Playing as Karthus against Vayne
Lay Waste is very strong at farming minions and harassing enemy champions.
Ask your allies to help point out when you should use Requiem to get kills in different lanes.
Advice to Win Against Vayne
Deny Vayne the opportunity to pin you against walls.
Vayne is fragile - turn the pressure up on her and she will be forced to play cautiously.
Karthus vs Vayne Counter Stats
How to Counter Vayne with Karthus in LoL
The stats provided here clarify several significant Karthus against Vayne counter statistics that can help us figure out the distinctions between the two. Karthus’s KDA ratio ([kills + assists] / deaths) of NaN is greater than Vayne’s KDA ratio of NaN, demonstrating that Karthus may be more central to his team's team fighting potential than Vayne..
Karthus often has a similar longest kill spree as his enemy does. On average, he receives more damage than Vayne. This typically indicates differing health capacities, yet it can also illustrate that the one champion has less agility and thus is unable to escape further harm when poked or engaged.
Differences between Karthus and Vayne
Damage Types Compared
Champion Playstyles Compared
Who is Better, Karthus or Vayne?
Both LoL champions are great champions. Both champs have their pros and cons. In the game's current meta, Karthus usually loses when taking on Vayne, with a 47.0% win rate. Thus, Karthus makes a bad counter to Vayne.
While Karthus does have a lower win rate compared to Vayne, when they face off with one another, Karthus also has a lower level of difficulty that makes him a less time consuming champ to learn. You should expect to face a difficult match when picking Karthus into Vayneas his relative depth means you may not be able to unleash his full potential without a lot of practice beforehand.
Moreover, Karthus also has some amount of utility and CC, a similar amount to Vayne. This often makes her just as valuable during team fights, especially when trying to counter champions with a lot of burst damage.
While there isn't a single best champion in League of Legends, in Karthus vs Vayne matchups, Vayne is the better champ with a much lower win rate, less champion complexity, and a similar amount of utility to help out your allies during team fights.
Karthus is a terribly counter for Vayne. You will do well by focussing your play on keeping up your CS and taking out objectives. If you are able to do that, you should hold your own as Karthus against Vayne.
Other Champion Matchups Against Karthus
Additional Information for Karthus Players
How We Calculated Our Karthus vs Vayne Build and Stats
Other Useful Resources
Further Insights to Win this Matchup
If you would like to truly master Karthus to counter Vayne during both the laning and mid / late game phases of League of Legends, you should keep reading to gather a few extra tricks and insights into this matchup. If you mind the build and stats presented above, you should increase your win rate by a lot and be closer to League of Legends pro players.
Karthus most often gets less CS as Vayne. Champions who typically don't acquire much CS usualy don't need much CS to be effective, such as support champions. These kinds of champions are able to scale well off of their abilities and first items alone. Yet, champs with large amounts of CS, such as hyper-carries, often need a lot of items to be effective. In either case, try to exceed the numbers reported on this page to do well.
The top items to focus on in your Karthus versus Vayne build include Rabadon's Deathcap, Void Staff, and Liandry's Torment. When Karthus combined at least these three items in his build, he performed significantly better vs Vayne than with many other commonly used builds. In fact, Karthus boasted an average winrate of 47.0% when playing against Vayne with this counter build.
To have the best likelihood of vanquishing Vayne as Karthus, you should take the Dark Harvest, Cheap Shot, Eyeball Collection, Ultimate Hunter, Presence of Mind, and Last Stand runes from the Domination and Precision rune sets. Out of all the rune sets that we analyzed for Karthus vs Vayne clashes, this combination of runes yielded the best win rate. Moreover, these runes gave a 47.0% winrate overall.
If you want to see Karthus x Vayne tips and matchup stats and build suggestions for a a particular skill level, please select one from the selection menu above. At first, the stats and strategies displayed are calculated using every game with data with both champions.