Lay Waste is very strong at farming minions and harassing enemy champions.
Ask your allies to help point out when you should use Requiem to get kills in different lanes.
Focus on dodging Wild Cards early when your champion doesn't have the hit points to afford getting hit.
If you have low Health, use Destiny as an indicator to run to safety. It will give you a head start in escaping any possible ganks.
The stats provided here underscore some important Karthus against Twisted Fate counter statistics that can help us understand the distinctions between the two. For instance, Karthus’s KDA ratio ([kills + assists] / deaths) of NaN is more than Twisted Fate’s ratio of NaN, highlighting that Karthus may be more central to his team's team fighting capability than Twisted Fate..
Karthus often has a similar longest kill spree as his matchup does. On average, he takes more damage than Twisted Fate. This often reflects differing health capacities; however, it can also illustrate that the one champion has less mobility and thus is unable to flee from further harm when engaged or poked.
Both LoL champions are great champions. Both have their pros and cons. In League's current meta, Karthus usually loses when playing against Twisted Fate, with a 46.7% win rate. Thus, Karthus makes a bad counter for Twisted Fate.
While Karthus does have a lower winrate compared to Twisted Fate, when on opposite teams, Karthus also has a lower difficulty level that makes him a less complex champ to pick up and master. You should expect to face a difficult match when picking Karthus into Twisted Fateas his relative depth means that you may not be able to unleash his full potential without a lot of practice beforehand.
Additionally, Karthus also has some amount of CC and other utility, a similar amount to Twisted Fate. This makes her just as valuable during team fights, especially when trying to counter champions with a lot of burst damage.
While there is not one best champion overall in League of Legends, in Karthus vs Twisted Fate matchups, Twisted Fate is the better champion with a much lower win rate, less champion complexity, and a similar amount of utility to help out your team members during teamfights.
Karthus is a terribly counter to Twisted Fate. Focus your gameplay on keeping up your CS and destroying objectives. If you can do that, you should hold your own as Karthus against Twisted Fate.
To truly master Karthus to counter Twisted Fate during both the lane and mid / late game phases of League of Legends, you should continue reading to gather a few extra lessons on this matchup. If you pay attention to the build and suggestions shown above, you should grow your win rate significantly and be that much closer to League of Legends pro players.
Karthus most often racks up less CS relative to Twisted Fate. Champions who typically don't take many minion kills often don't have to have much CS to be effective, such as support champions. They are capable of scaling well off of their skills, stats, and first items alone. Yet, champs with a lot of CS, such as hyper-carries, typically need a lot of items to be effective. In either situation, try to exceed the values displayed on this page to do well.
The ideal items to focus on in your Karthus versus Twisted Fate build consist of Rabadon's Deathcap, Malignance, and Liandry's Torment. When Karthus bought at least these three items in his build, he did a lot better countering Twisted Fate than with many other commonly used item sets. In fact, Karthus had an average winrate of 46.7% when countering Twisted Fate with this counter build.
To have the highest chance of defeating Twisted Fate as Karthus, Karthus players should equip the Dark Harvest, Cheap Shot, Eyeball Collection, Ultimate Hunter, Presence of Mind, and Last Stand runes from the Domination and Precision rune sets. Out of all the runes that we analyzed for Karthus vs Twisted Fate counters, this mix of runes resulted in the best win rate. Notably, these runes gave a 46.7% winrate overall.
By default, tips, statistics, and builds on how to beat Twisted Fate as Karthus are displayed for all ranked divisions combined. If you would like to narrow the stats and builds to a specific player tier, you may use the selection menu above.