Lay Waste is very strong at farming minions and harassing enemy champions.
Ask your allies to help point out when you should use Requiem to get kills in different lanes.
Intentionally breaking a wall of The Box can allow a vulnerable ally to escape unscathed.
Thresh's Death Sentence has a long cast time. Watch for the cast to begin to take evasive actions.
Thresh relies on collecting souls for a portion of his defense and damage. Try punishing him when he moves to collect them.
The stats provided here clarify some significant Karthus versus Thresh counter stats that can help you understand the differences between these two champions. As an example, Karthus’s KDA ratio ([kills + assists] / deaths) of NaN is better than Thresh’s KDA ratio of NaN, indicating that Karthus may be more central to his team's team fighting potential than Thresh. This observation is largely a result of the difference in kills.
Karthus usually has a much larger longest kill spree than his counter does. Commonly, he receives more damage than Thresh. This typically indicates different amounts of tankyness, but it can also hint that the one champ has less mobility and thus is unable to flee from further damage when poked or engaged.
Both League champs are great. Both champs have their pros and cons. In League's current meta, Karthus usually fairs equally well when taking on Thresh, with a 49.6% win rate. Thus, Karthus makes an ok counter to Thresh.
While Karthus does have a lower winrate than Thresh, when they face off with one another, Karthus also has a greater difficulty level that makes him a more complex champ to develop with. You should be careful when picking Karthus into Threshas his relative depth means that you may not be able to reach his full potential without a lot of practice beforehand.
Moreover, Karthus has some amount of CC and other utility, a similar amount to Thresh. This makes her just as valuable during team fights, especially when facing champions with a ton of burst damage.
While there isn't one best champion for every situation in League of Legends, in Karthus vs Thresh matchups, Thresh is the better champ with a similar win rate, similar champion depth, and a similar amount of utility to help out your teammates during late stage team fights.
Karthus is a somewhat poor counter to Thresh. Focus your strategy on maximizing your gold income and taking out objectives. If you are able to do that, you should hold your own as Karthus against Thresh.
If you would like to learn all of the intricacies of Karthus in order to counter Thresh during both the lane and mid / late game phases of League of Legends, you should keep reading to pick up a few extra tricks and insights into this matchup. If you listen to the build and suggestions displayed here, you will grow your win rate by a lot and be closer to League of Legends pro players.
Karthus often accumulates more CS relative to Thresh. Champions who typically don't take many minion kills typically don't need much CS to be effective, such as supports. They are able to scale well off of their abilities and first items alone. Yet, champions with large amounts of CS, such as hyper-carries, usually require a lot of items to be effective. In either case, try to exceed the values displayed here to do well.
The top items to focus on in your Karthus versus Thresh build consist of Rabadon's Deathcap, Malignance, and Stormsurge. When Karthus combined at least these three pieces in his build, he performed a lot better countering Thresh than with many other common counter builds. In fact, Karthus boasted an average winrate of 49.6% when countering Thresh with this counter build.
To have the best probability of defeating Thresh as Karthus, you should take the First Strike, Magical Footwear, Future's Market, Cosmic Insight, Eyeball Collection, and Ultimate Hunter runes from the Inspiration and Domination rune sets. Of all the rune sets players used for Karthus vs Thresh counter picks, this blending of runes resulted in the greatest win rate. In fact, these runes averaged a 49.6% win rate overall.
By default, tips, statistics, and builds on how to beat Thresh as Karthus are presented for all skill levels, merged. If you would like to scope the stats and builds to a specific rank, you should use the selection menu located above.